Abstract 1149: Targeting Rad6B suppresses melanomagenesis
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DOI: 10.1158/1538-7445.am2017-1149
Abstract: Active β-catenin signaling in melanoma is associated with aggressive disease. We have previously shown that Rad6B, an ubiquitin conjugating enzyme, is a positive regulator of β-catenin stability and transcriptional activity, and is itself a transcriptional… read more here.
Keywords: melanoma; catenin; rad6b; rad6b suppresses ... See more keywords