Astrocytes and radial glia‐like cells, but not neurons, display a nonapoptotic increase in caspase‐3 expression following exercise
Sign Up to like & getrecommendations! Published in 2018 at "Brain and Behavior"
DOI: 10.1002/brb3.1110
Abstract: Exercise induces plasticity in the hippocampus, which includes increases in neurogenesis, the proliferation of new neurons, and angiogenesis, the sprouting of new capillaries from preexisting blood vessels. Following exercise, astrocytes also undergo morphological changes that… read more here.
Keywords: radial glia; following exercise; glia like; exercise astrocytes ... See more keywords
Radial glia in the zebrafish brain: Functional, structural, and physiological comparison with the mammalian glia
Sign Up to like & getrecommendations! Published in 2020 at "Glia"
DOI: 10.1002/glia.23849
Abstract: The neuroscience community has witnessed a tremendous expansion of glia research. Glial cells are now on center stage with leading roles in the development, maturation, and physiology of brain circuits. Over the course of evolution,… read more here.
Keywords: radial glia; physiology; zebrafish brain; glia radial ... See more keywords
Lipoprotein receptor loss in forebrain radial glia results in neurological deficits and severe seizures
Sign Up to like & getrecommendations! Published in 2020 at "Glia"
DOI: 10.1002/glia.23869
Abstract: The Alzheimer disease‐associated multifunctional low‐density lipoprotein receptor‐related protein‐1 is expressed in the brain. Recent studies uncovered a role of this receptor for the appropriate functioning of neural stem cells, oligodendrocytes, and neurons. The constitutive knock‐out… read more here.
Keywords: radial glia; density; receptor; lipoprotein receptor ... See more keywords
Transcriptome analysis reveals the contribution of oligodendrocyte and radial glia‐derived cues for maintenance of microglia identity
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DOI: 10.1002/glia.24136
Abstract: Microglia are increasingly being recognized as druggable targets in neurodegenerative disorders, and good in vitro models are crucial to address cell biological questions. Major challenges are to recapitulate the complex microglial morphology and their in… read more here.
Keywords: analysis; derived cues; oligodendrocyte radial; glia derived ... See more keywords
Dedifferentiation of radial glia-like cells is observed in in vitro explants of holothurian radial nerve cord
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2021.109358
Abstract: BACKGROUND Among animal phyla, some of the least studied nervous systems are those of the phylum Echinodermata. Part of the problem lies in that most of their nervous components are embedded in the body wall… read more here.
Keywords: radial glia; glia like; dedifferentiation radial; radial nerve ... See more keywords
Neurogenic Radial Glia-like Cells in Meninges Migrate and Differentiate into Functionally Integrated Neurons in the Neonatal Cortex.
Sign Up to like & getrecommendations! Published in 2017 at "Cell stem cell"
DOI: 10.1016/j.stem.2016.10.020
Abstract: Whether new neurons are added in the postnatal cerebral cortex is still debated. Here, we report that the meninges of perinatal mice contain a population of neurogenic progenitors formed during embryonic development that migrate to… read more here.
Keywords: radial glia; cortex; like cells; glia like ... See more keywords
Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma.
Sign Up to like & getrecommendations! Published in 2020 at "Cell stem cell"
DOI: 10.1016/j.stem.2019.11.015
Abstract: Glioblastoma is a devastating form of brain cancer. To identify aspects of tumor heterogeneity that may illuminate drivers of tumor invasion, we created a glioblastoma tumor cell atlas with single-cell transcriptomics of cancer cells mapped… read more here.
Keywords: radial glia; glioblastoma; outer radial; cancer ... See more keywords
Adult Human Glioblastomas Harbor Radial Glia-like Cells
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2020.01.007
Abstract: Summary Radial glia (RG) cells are the first neural stem cells to appear during embryonic development. Adult human glioblastomas harbor a subpopulation of RG-like cells with typical RG morphology and markers. The cells exhibit the… read more here.
Keywords: radial glia; human glioblastomas; adult human; like cells ... See more keywords
Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.
Sign Up to like & getrecommendations! Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-29302-8
Abstract: Astroblastomas (ABs) are rare brain tumors of unknown origin. We performed an integrative genetic and epigenetic analysis of AB-like tumors. Here, we show that tumors traceable to neural stem/progenitor cells (radial glia) that emerge during… read more here.
Keywords: inactivation escape; radial glia; exhibit; stem ... See more keywords
Isolation, Propagation, and Differentiation of Radial Glia-Like Neural Progenitor Cells in Adherent Cultures.
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DOI: 10.1101/pdb.prot094177
Abstract: This protocol describes the isolation of radial glia-like neural progenitors (RGLs) from embryonic and adult mouse brain. Their propagation as an adherent monolayer is greatly supported by use of the AK-cyclo(RGDfC) adhesive peptide-conjugate that allows… read more here.
Keywords: radial glia; isolation propagation; glia like; like neural ... See more keywords
Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm6340
Abstract: Glioblastoma is believed to originate from nervous system cells; however, a putative origin from vessel-associated progenitor cells has not been considered. We deeply single-cell RNA–sequenced glioblastoma progenitor cells of 18 patients and integrated 710 bulk… read more here.
Keywords: neural network; perivascular radial; glioblastoma; neural crest ... See more keywords