Synaptic transmission from subplate neurons controls radial migration of neocortical neurons
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.aar2866
Abstract: Transient instruction changes migration The brain neocortex is built by waves of neurons migrating from deep within the brain to the surface layers. Ohtaka-Maruyama et al. found that a layer of neurons that multipolar neurons… read more here.
Keywords: subplate; subplate neurons; synaptic transmission; multipolar neurons ... See more keywords
Fbxo45 Binds SPRY Motifs in the Extracellular Domain of N-Cadherin and Regulates Neuron Migration during Brain Development
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DOI: 10.1128/mcb.00539-19
Abstract: Several events during the normal development of the mammalian neocortex depend on N-cadherin, including the radial migration of immature projection neurons into the cortical plate. Remarkably, radial migration requires the N-cadherin extracellular domain but not… read more here.
Keywords: cadherin; domain cadherin; radial migration; extracellular domain ... See more keywords
Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-019-0827-y
Abstract: For the proper organization of the six-layered mammalian neocortex it is required that neurons migrate radially from their place of birth towards their designated destination. The molecular machinery underlying this neuronal migration is still poorly… read more here.
Keywords: migration; upper layer; radial migration; cortical neurons ... See more keywords
RNA Binding Protein Rbms1 Enables Neuronal Differentiation and Radial Migration during Neocortical Development by Binding and Stabilizing the RNA Message for Efr3a
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DOI: 10.14348/molcells.2022.0044
Abstract: Various RNA-binding proteins (RBPs) are key components in RNA metabolism and contribute to several neurodevelopmental disorders. To date, only a few of such RBPs have been characterized for their roles in neocortex development. Here, we… read more here.
Keywords: efr3a; radial migration; development; rbms1 ... See more keywords
Radial Migration Dynamics Is Modulated in a Laminar and Area-Specific Manner During Primate Corticogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.588814
Abstract: The orderly radial migration of cortical neurons from their birthplace in the germinal zones to their final destination in the cortical plate is a prerequisite for the functional assembly of microcircuits in the neocortex. Rodent… read more here.
Keywords: primate corticogenesis; migrating neurons; neurons destined; area ... See more keywords