LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "radiation attenuated" as a keyword



Plasmodium berghei Radiation‐Attenuated Sporozoite‐Immunized Mice Require Infectious Sporozoite Challenge to Maintain Protective Immunity

Sign Up to like & get
recommendations! Published in 2025 at "European Journal of Immunology"

DOI: 10.1002/eji.202451542

Abstract: Plasmodium radiation‐attenuated sporozoites (RAS) confer sterile protection in mammalian hosts. The duration of protection is affected by the dose of RAS, the route of immunization, and the timing of primary challenge (PC). Giving PC shortly… read more here.

Keywords: protection; radiation attenuated; cd8 cells; plasmodium berghei ... See more keywords

Nonreciprocity of thermal radiation in attenuated total reflection‐mediated optical waveguide

Sign Up to like & get
recommendations! Published in 2024 at "Microwave and Optical Technology Letters"

DOI: 10.1002/mop.34345

Abstract: Fano resonance (FR) and the triggered nonreciprocal thermal radiation (NTR) in a Weyl semimetal (WSM)‐ incorporated Kretschmann configuration has been observed and analyzed. Employing the anisotropic permittivity tensor, the electromagnetic responses of the proposed layered… read more here.

Keywords: nonreciprocity thermal; thermal radiation; radiation; radiation attenuated ... See more keywords

Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

Sign Up to like & get
recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-53118-9

Abstract: Radiation-attenuated sporozoite (RAS) vaccines can completely prevent blood stage Plasmodium infection by inducing liver-resident memory CD8+ T cells to target parasites in the liver. Such T cells can be induced by ‘Prime-and-trap’ vaccination, which here… read more here.

Keywords: adjuvant 7dw8; glycolipid adjuvant; administration; ultra low ... See more keywords

Long lived liver-resident memory T cells of biased specificities for abundant sporozoite antigens drive malaria protection by radiation-attenuated sporozoite vaccination

Sign Up to like & get
recommendations! Published in 2024 at "PLOS Pathogens"

DOI: 10.1371/journal.ppat.1012731

Abstract: Vaccination with radiation-attenuated sporozoites (RAS) can provide highly effective protection against malaria in both humans and mice. To extend understanding of malaria immunity and inform the development of future vaccines, we studied the protective response… read more here.

Keywords: protection; memory; vaccination; memory cells ... See more keywords

Longitudinal immune profiling after radiation-attenuated sporozoite vaccination reveals coordinated immune processes correlated with malaria protection

Sign Up to like & get
recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1042741

Abstract: Background Identifying immune processes required for liver-stage sterilizing immunity to malaria remains an open problem. The IMRAS trial comprised 5x immunizations with radiation-attenuated sporozoites resulting in 55% protection from subsequent challenge. Methods To identify correlates… read more here.

Keywords: immune processes; protection; vaccination; malaria ... See more keywords