Radical Approach to the Chiral Quaternary Center in Asperaculin A: Synthesis of 9-Deoxyasperaculin A.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.6b03854
Abstract: Diastereoselective approaches toward the synthesis of a marine-derived sesquiterpenoid fungal metabolite, asperaculin A, are delineated, combining step economy and simplicity. Two distinct lactonization sequences from a common intermediate led to the first synthesis of 9-deoxyasperaculin… read more here.
Keywords: asperaculin; approach chiral; synthesis deoxyasperaculin; radical approach ... See more keywords
A radical approach for the selective C-H borylation of azines.
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03637-6
Abstract: Boron functional groups are often introduced in place of aromatic carbon-hydrogen bonds to expedite small-molecule diversification through coupling of molecular fragments1-3. Current approaches based on transition metal-catalysed C-H activation are effective for the borylation of… read more here.
Keywords: borylation; borylation azines; radical approach; approach ... See more keywords
Names above the rank of genus; the radical approach.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of systematic and evolutionary microbiology"
DOI: 10.1099/ijsem.0.003169
Abstract: The International Code of Nomenclature of Prokaryotes currently caters for the names of ranks from class to subspecies. The form of names and their typification is dealt with under Rules 7-22. The nature of names… read more here.
Keywords: genus radical; radical approach; microbiology; rank genus ... See more keywords
The radical approach to the oligometastatic not small cell lung cancer patient: which? how? when? where?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2019.06.28
Abstract: In 1894, Halsted defined that a primary tumour spread first through lymphatics vessels to lymph nodes and then to distant organs. Hellman argued that cancer, even at the time of diagnosis, is a biologic variety… read more here.
Keywords: small cell; cancer; radical approach; approach oligometastatic ... See more keywords
Cerium oxide nanoparticles: a 'radical' approach to neurodegenerative disease treatment.
Sign Up to like & getrecommendations! Published in 2017 at "Nanomedicine"
DOI: 10.2217/nnm-2016-0399
Abstract: Despite advances in understanding the factors that cause many neurodegenerative diseases (NDs), no current therapies have yielded significant results. Cerium oxide nanoparticles (CeONPs) have recently emerged as therapeutics for the treatment of NDs due to… read more here.
Keywords: cerium oxide; oxide nanoparticles; treatment; nanoparticles radical ... See more keywords