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Published in 2022 at "eLife"
DOI: 10.1101/2022.09.12.22279840
Abstract: Background: Tafenoquine is a newly licensed antimalarial drug for the radical cure of Plasmodium vivax malaria. The mechanism of action and the optimal dosing - a balance between haemolytic risk and radical cure efficacy -…
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Keywords:
pharmacology;
vivax malaria;
radical cure;
increase ... See more keywords
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Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0275822
Abstract: Introduction Cambodia aims to eliminate malaria by 2025, however tackling Plasmodium vivax (P.v) presents multiple challenges. The prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency has prevented the deployment of 8-aminoquinolones for “radical cure”, due to the…
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Keywords:
radical cure;
g6pd;
cambodia;
g6pd testing ... See more keywords