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Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02109
Abstract: A method for facile difluoromethylation of various thiols using (difluoromethyl)triphenylphosphonium bromide under mild reaction conditions is presented. The transformation proceeds in the absence of any transition metal using a bench-stable and readily accessible phosphonium salt.…
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Keywords:
thiols difluoromethyl;
difluoromethylation thiols;
radical difluoromethylation;
difluoromethyl triphenylphosphonium ... See more keywords