A powerful approach to alkoxy radical-mediated remote C(sp3)–H bonds functionalization
Sign Up to like & getrecommendations! Published in 2018 at "Science China Chemistry"
DOI: 10.1007/s11426-018-9222-6
Abstract: The activation of inert C(sp)–H bonds with control of reactivity and selectivity is one of the central topics in chemical sciences. In this context, alkoxy radical-mediated 1,5hydrogen atom transfer allows the regioselective transformation of inert… read more here.
Keywords: powerful approach; alkoxy radicals; bond; chemistry ... See more keywords
Recent advances in radical-mediated [2+2+m] annulation of 1,n-enynes
Sign Up to like & getrecommendations! Published in 2019 at "Science China Chemistry"
DOI: 10.1007/s11426-019-9615-0
Abstract: 1,n-Enynes are a versatile class of unsaturated hydrocarbons that find broad applications in the synthetic community of natural products, biologically active structures and functional materials. Typical methods for the transformations of 1,n-enynes include the radical-mediated… read more here.
Keywords: annulation enynes; mediated annulation; radical mediated; advances radical ... See more keywords
Kinetics and mechanism of reactive radical mediated fluconazole degradation by the UV/chlorine process: Experimental and theoretical studies
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2020.126224
Abstract: Abstract The emerging organic contaminants can be effectively removed in the UV/chlorine process by produced hydroxyl radical (HO ) and chlorine-derived radicals (Cl , ClO , etc.). However, the degradation mechanism and pathways of reactive… read more here.
Keywords: reactive radical; degradation; chlorine process; radical mediated ... See more keywords
A chloride-radical-mediated electrochemical filtration system for rapid and effective transformation of ammonia to nitrogen.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.04.180
Abstract: Water contamination from ammonia has recently became a global concern. Herein, a chloride-radical-mediated electrochemical filtration system has been developed towards effective and rapid conversion of ammonia to nitrogen (N2). This continuous-flow system consists of a… read more here.
Keywords: mediated electrochemical; electrochemical filtration; system; ammonia ... See more keywords
Synthesis of gem-Disulfonyl Enamines via an Iminyl-Radical-Mediated Formal 1,3-HAT/Radical Coupling Cascade.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02277
Abstract: We herein report the first example of an iminyl-radical-mediated formal 1,3-HAT/radical coupling cascade of vinyl azides leading to the synthesis of tetrasubstituted gem-disulfonyl enamines. It is possible to employ a variety of vinyl azides and… read more here.
Keywords: mediated formal; iminyl radical; hat radical; radical coupling ... See more keywords
Photoinduced Remote C(sp3)-H Imination Enabled by Vinyl Radical-Mediated 1,5-Hydrogen Atom Transfer.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00510
Abstract: A vinyl radical-mediated 1,5-hydrogen atom transfer strategy for remote C(sp3)-H imination under visible-light-induced photochemical metal-free conditions afforded diverse γ-imino alkenes with excellent stereoselectivity. Oxime ester-based bifunctional reagents provided not only nucleophilic alkyl radicals for radical… read more here.
Keywords: hydrogen atom; hydrogen; mediated hydrogen; atom transfer ... See more keywords
Radical-Mediated Heck-Type Alkylation: Stereoconvergent Synthesis of Functionalized Polyenes.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b02838
Abstract: The stereospecific synthesis of polyenes is of great synthetic value. Disclosed herein is a new, efficient, stereoconvergent approach for the synthesis of functionalized polyenes via a radical-mediated Heck-type alkylation. The easily accessed Z- and E-mixed… read more here.
Keywords: synthesis functionalized; heck type; radical mediated; functionalized polyenes ... See more keywords
Density Functional Theory Guide for an Allyl Monomer Polymerization Mechanism: Photoinduced Radical-Mediated [3 + 2] Cyclization
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c00165
Abstract: Polymerization of allyl ether monomers has previously been considered a free-radical addition polymerization mechanism, but it is difficult to achieve because of the high electron density of their double bond. To interpret the mechanism of… read more here.
Keywords: allyl ether; mechanism; mediated cyclization; radical mediated ... See more keywords
Radical-Mediated Strategies for the Functionalization of Alkenes with Diazo Compounds.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c05183
Abstract: One of the most common reactions of diazo compounds with alkenes is cyclopropanation that occurs through metal carbene or free carbene intermediates. Alternative functionalization of alkenes with diazo compounds is limited, and methodology for the… read more here.
Keywords: carbon; diazo compounds; radical mediated; alkenes diazo ... See more keywords
Radical S-Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c12010
Abstract: The biosynthesis of blasticidin S has drawn attention due to the participation of the radical S-adenosyl methionine (SAM) enzyme BlsE. The original assignment of BlsE as a radical-mediated, redox-neutral decarboxylase is unusual because this reaction… read more here.
Keywords: biosynthesis blasticidin; dehydration; enzyme blse; adenosyl methionine ... See more keywords
Reduced-Phenalenyl-Based Molecule as a Super Electron Donor for Radical-Mediated C-N Coupling Catalysis at Room Temperature.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c09225
Abstract: We demonstrate that an in situ generated di-reduced phenalenyl (PLY) species accumulates sufficiently high energy and acts as a super electron donor to generate aryl radicals from aryl halides to accomplish Buchwald-Hartwig-type C-N cross-coupling reactions… read more here.
Keywords: electron donor; super electron; reduced phenalenyl; electron ... See more keywords