Photocatalytic C-Si Bond Formations Using Pentacoordinate Silylsilicates as Silyl Radical Precursors: Synthetic Tricks Using Old Reagents.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00096
Abstract: A visible-light-induced photocatalytic C-Si formation strategy has been disclosed by uncovering the reactivity of Martin's spirosilane-derived pentacoordinate silylsilicates as silyl radical precursors. The hydrosilylation of a broad spectrum of alkenes and alkynes, as well as… read more here.
Keywords: photocatalytic bond; silylsilicates silyl; pentacoordinate silylsilicates; radical precursors ... See more keywords
Tertiary Alcohols as Radical Precursors for the Introduction of Tertiary Substituents into Heteroarenes
Sign Up to like & getrecommendations! Published in 2019 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b00405
Abstract: Despite many recent advances in the radical alkylation of electron-deficient heteroarenes since the seminal reports by Minisci and co-workers, methods for the direct incorporation of tertiary alkyl substituents into nitrogen heteroarenes are limited. This report… read more here.
Keywords: introduction tertiary; radical precursors; alcohols radical; tertiary substituents ... See more keywords
The Application of Sulfonyl Hydrazides in Electrosynthesis: A Review of Recent Studies
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DOI: 10.1021/acsomega.2c04205
Abstract: Sulfonyl hydrazides are viewed as alternatives to sulfinic acids and their salts or sulfonyl halides, which are broadly used in organic synthesis or work as active pharmaceutical substances. Generally, sulfonyl hydrazides are considered good building… read more here.
Keywords: application sulfonyl; sulfonyl hydrazides; radical precursors; hydrazides electrosynthesis ... See more keywords
Boronic Acids and Their Derivatives as Continuous-Flow-Friendly Alkyl Radical Precursors
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DOI: 10.1055/a-2068-6038
Abstract: Since its recognition as an enabling tool to form challenging C-C and C-heteroatom bonds under mild and sustainable conditions, photoredox catalysis has been in the spotlight within the synthetic community. As a consequence, the interest… read more here.
Keywords: alkyl radical; boronic acids; acids derivatives; radical precursors ... See more keywords
Recent Progresses in Cancer Nanotherapeutics Design Using Artemisinins as Free Radical Precursors
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2020.00472
Abstract: Artemisinin and its derivatives (ARTs) are sort of important antimalarials, which exhibit a wide range of biological activities including anticancer effect. To solve the issues regarding poor solubility and limited bioavailability of ARTs, nanoformulation of… read more here.
Keywords: recent progresses; radical precursors; progresses cancer; arts activation ... See more keywords