Radical Strategy Towards N‐glycosides: Current Advances and Future Prospects
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DOI: 10.1002/cbic.202400864
Abstract: N‐glycosides exhibit diverse biological and pharmacological activities, making their efficient synthesis crucial for both biological research and drug development. Traditional acid‐promoted N‐glycosylation methods, which rely on the formation of oxocarbenium intermediates, often face significant challenges.… read more here.
Keywords: radical strategy; towards glycosides; strategy towards; glycosides current ... See more keywords
Radical Strategy to the Boron-to-Copper Transmetalation Problem: N‑Alkylation with Alkylboronic Esters
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DOI: 10.1021/jacs.5c07856
Abstract: Organoboron compounds represent highly versatile reagents in organic synthesis, but their application to forge C(sp3)–heteroatom bonds, particularly C(sp3)–N coupling, remains underdeveloped. While the integration of alkylboron reagents with copper catalysis offers a promising approach, the… read more here.
Keywords: boron copper; radical strategy; boron; copper ... See more keywords