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Hydroxyurea Scavenges Free Radicals and Induces the Expression of Antioxidant Genes in Human Cell Cultures Treated With Hemin

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Published in 2020 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2020.01488

Abstract: The excessive release of heme during hemolysis contributes to the severity of sickle cell anemia (SCA) by exacerbating hemoglobin S (HbS) autoxidation, inflammation and systemic tissue damage. The present study investigated the effect of hydroxyurea… read more here.

Keywords: treated hemin; free radicals; genes human; antioxidant genes ... See more keywords