Radio-pathomic maps of glioblastoma identify phenotypes of non-enhancing tumor infiltration associated with bevacizumab treatment response
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-024-04593-7
Abstract: Autopsy-based radio-pathomic maps of glioma pathology have shown substantial promise inidentifying areas of non-enhancing tumor presence, which may be able to differentiate subsets of patients that respond favorably to treatments such as bevacizumab that have… read more here.
Keywords: treatment; non enhancing; tumor; enhancing tumor ... See more keywords
Radio-pathomic estimates of cellular growth kinetics predict survival in recurrent glioblastoma
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DOI: 10.1080/20450907.2024.2415285
Abstract: Aim: A radio-pathomic machine learning (ML) model has been developed to estimate tumor cell density, cytoplasm density (Cyt) and extracellular fluid density (ECF) from multimodal MR images and autopsy pathology. In this multicenter study, we… read more here.
Keywords: treatment; post treatment; predict survival; radio pathomic ... See more keywords
Multi-site retrospective analysis of diffusion and perfusion magnetic resonance imaging correlates to glioma characteristics derived from radio-pathomic maps
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf044
Abstract: Abstract Background This study determines the relationship between diffusion and perfusion-based magnetic resonance imaging signatures and radio-pathomic maps of tumor pathology in a large, multi-site cohort. Methods This study included perfusion imaging from presurgical relative… read more here.
Keywords: pathology; perfusion; density; radio pathomic ... See more keywords
IMG-102. Radio-pathomic assessment of tumor dynamics following radiotherapy in glioblastoma patients
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.1181
Abstract: Following initial surgical resection, glioblastoma patients typically receive radiotherapy with adjuvant temozolomide to treat the resection cavity and non-enhancing areas beyond its margin. However, radiotherapy’s impact on traditional imaging signatures can confound the interpretation of… read more here.
Keywords: radio pathomic; radiotherapy; glioblastoma patients; non enhancing ... See more keywords
504 90th Percentile: Long-Term Glioblastoma Survivors Display Favorable Preoperative Radio-Pathomic Maps of Tumor Cell Density
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DOI: 10.1227/neu.0000000000003360_504
Abstract: INTRODUCTION: Glioblastoma (GBM) is the most common primary CNS malignancy, with one- and five-year survival rates of 41% and 5%, respectively. Extent of resection correlates with increased survival, but tools to predict long-term survivors (LTS)… read more here.
Keywords: cell density; long term; tumor; radio pathomic ... See more keywords
Radio-Pathomic Maps of Cell Density Identify Brain Tumor Invasion beyond Traditional MRI-Defined Margins
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a7477
Abstract: A radio-pathomic model for cellularity trained with tissue samples acquired at postmortem examination is able to identify regions of hypercellular tumor beyond traditional imaging signatures. BACKGROUND AND PURPOSE: Currently, contrast-enhancing margins on T1WI are used… read more here.
Keywords: beyond traditional; radio pathomic; tissue samples; cellularity ... See more keywords