A lectin-based glycomic approach identifies FUT8 as a driver of radioresistance in oesophageal squamous cell carcinoma
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DOI: 10.1007/s13402-020-00517-5
Abstract: Purpose Radio-resistance is recognized as a main factor in the failure of radiotherapy in oesophageal squamous cell carcinoma (ESCC). Aberrant cell surface glycosylation has been reported to correlate with radio-resistance in different kinds of tumours.… read more here.
Keywords: radio resistance; lectin based; cell; escc ... See more keywords
Overcoming radio-resistance in esophageal squamous cell carcinoma via hypermethylation of PIK3C3 promoter region mediated by KDM5B loss
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DOI: 10.1093/jrr/rrac004
Abstract: Abstract Many patients with esophageal squamous cell carcinoma (ESCC) are inoperable because of old age or the advanced stage of the disease; thus radio- and chemotherapy are believed as the standard treatments for these patients.… read more here.
Keywords: cell; pik3c3; radio resistance; esophageal squamous ... See more keywords
Epigenetic regulation of RARB overcomes the radio-resistance of colorectal carcinoma cells via cancer stem cells
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DOI: 10.1093/jrr/rrac060
Abstract: Abstract Cancer stem cells (CSCs) are able to survive after cancer therapies, leading to cancer progression and recurrence in colorectal carcinoma (CRC). Therapies targeting CSCs are believed to be promising strategies for efficiently eradicating cancers.… read more here.
Keywords: radio resistance; cancer stem; colorectal carcinoma; stem cells ... See more keywords
Radio-Resistance and DNA Repair in Pediatric Diffuse Midline Gliomas
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DOI: 10.3390/cancers12102813
Abstract: Simple Summary Approximately 50% of high-grade gliomas (HGG) in children are diffuse midline gliomas (DMGs), which carry the worst prognosis of all HGG, with a 2-year survival of less than 10%. DMGs are characterized by… read more here.
Keywords: gliomas; radio resistance; diffuse midline; resistance ... See more keywords
Counteracting Radio-Resistance Using the Optimization of Radiotherapy
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DOI: 10.3390/ijms21051767
Abstract: Radiotherapy is an essential component of cancer therapy and remains one of the most (cost-) effective treatment options available [...]. read more here.
Keywords: counteracting radio; radio resistance; radiotherapy; using optimization ... See more keywords