Radiofluorination of a NHC-PF5 adduct: toward new probes for 18F PET imaging.
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DOI: 10.1039/c7cc04402j
Abstract: The radiofluorination of N-heterocyclic carbene (NHC) phosphorus(v) fluoride adducts has been investigated. The results show that the IMe-PF5 derivative (IMe = 1,3-dimethylimidazol-2-ylidene) undergoes a Lewis acid promoted 18F-19F isotopic exchange. The resulting radiofluorinated probe is… read more here.
Keywords: toward new; nhc pf5; radiofluorination nhc; pf5 adduct ... See more keywords
Organocatalyst-assisted Ar-18F bond formation: a universal procedure for direct aromatic radiofluorination.
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DOI: 10.1039/c7cc07211b
Abstract: A metal free, phosphane-catalysed protocol for C-F bond formation based on ipso-elimination of iodanes is described. The reaction proceeds in significantly higher yield and with markedly reduced variability of yields (yield range) than previously described… read more here.
Keywords: bond formation; bond; organocatalyst assisted; assisted 18f ... See more keywords