Treatment-resistant synovitis and radiographic progression are increased in elderly-onset rheumatoid arthritis patients: findings from a prospective observational longitudinal early arthritis cohort study.
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in arthritis and rheumatism"
DOI: 10.1016/j.semarthrit.2020.03.018
Abstract: BACKGROUND Clinical outcomes in elderly-onset rheumatoid arthritis (EORA), starting after the age of 60, are conflicting. Thus, we aimed to investigate in a unique biopsy-driven, treatment-naïve early arthritis cohort, the relationship between synovial pathobiology of… read more here.
Keywords: synovitis; onset rheumatoid; treatment; radiographic progression ... See more keywords
Do NSAIDs affect radiographic progression in axial SpA?
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DOI: 10.1038/s41584-019-0341-4
Abstract: NSAIDs are first line therapy for patients with axial spondyloarthritis and are recommended to be taken continuously in patients with active disease, but their ability to affect radiographic disease progression has been uncertain. Does a… read more here.
Keywords: progression axial; radiographic progression; nsaids affect; axial spa ... See more keywords
Baseline MRI bone erosion predicts the subsequent radiographic progression in early rheumatoid arthritis patients who achieved sustained good clinical response
Sign Up to like & getrecommendations! Published in 2017 at "Modern Rheumatology"
DOI: 10.1080/14397595.2017.1294280
Abstract: Abstract Objective: To examine whether magnetic resonance imaging (MRI) findings at baseline predict radiographic progression in early-stage rheumatoid arthritis (RA) patients who have achieved sustained good clinical response. Methods: This is a sub-analysis from the… read more here.
Keywords: arthritis; radiographic progression; baseline; bone erosion ... See more keywords
Biomarkers for treatment change and radiographic progression in patients with rheumatoid arthritis in remission: a 5 year follow-up study.
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology"
DOI: 10.1093/rheumatology/keaa258
Abstract: OBJECTIVE To identify biomarkers of treatment change and radiographic progression in patients with RA under remission. PATIENTS AND METHODS RA patients in remission (DAS28-ESR 10.47 (small detectable change). RESULTS Sixty patients were included, 81.6% were… read more here.
Keywords: change; year; remission; radiographic progression ... See more keywords
A replication study and meta-analysis of mitochondrial DNA variants in the radiographic progression of knee osteoarthritis
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology"
DOI: 10.1093/rheumatology/kew394
Abstract: Objective. To conduct a replication study and meta-analysis involving the study of mtDNA variants in the radiographic progression of OA in different cohorts worldwide, including Cohort Hip and Cohort Knee (CHECK), the OA Initiative and… read more here.
Keywords: rate radiographic; analysis; radiographic progression; knee ... See more keywords
Grade and location of power Doppler are predictive of damage progression in rheumatoid arthritis patients in clinical remission by anti-tumour necrosis factor &agr;
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology"
DOI: 10.1093/rheumatology/kex084
Abstract: Objectives To investigate power Doppler (PD) signal, grade and location and their association with radiographic progression in RA patients in remission. Methods A prospective observational study was conducted in 125 consecutive RA patients in stable… read more here.
Keywords: location; grade location; remission; radiographic progression ... See more keywords
A simplified radiographic score effectively predicts radiographic progression of early arthritis in a large nationwide French cohort.
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology"
DOI: 10.1093/rheumatology/kez450
Abstract: OBJECTIVE Evaluating radiographic progression is a key component of the follow-up of patients with RA. Existing scores are ill-suited to everyday clinical practice. The objective here was to validate a new simplified radiographic score (SRS)… read more here.
Keywords: radiographic progression; radiographic score; simplified radiographic; early arthritis ... See more keywords
TNF blockers inhibit spinal radiographic progression in ankylosing spondylitis by reducing disease activity: results from the Swiss Clinical Quality Management cohort
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-211544
Abstract: Objectives To analyse the impact of tumour necrosis factor inhibitors (TNFis) on spinal radiographic progression in ankylosing spondylitis (AS). Methods Patients with AS in the Swiss Clinical Quality Management cohort with up to 10 years… read more here.
Keywords: ankylosing spondylitis; radiographic progression; disease activity; spinal radiographic ... See more keywords
Secukinumab improves active psoriatic arthritis symptoms and inhibits radiographic progression: primary results from the randomised, double-blind, phase III FUTURE 5 study
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DOI: 10.1136/annrheumdis-2017-212687
Abstract: Objectives To evaluate the effect of subcutaneous (s.c.) secukinumab, an interleukin-17A inhibitor, on clinical signs and symptoms and radiographic progression in patients with psoriatic arthritis (PsA). Methods Adults (n=996) with active PsA were randomised 2:2:2:3… read more here.
Keywords: psoriatic arthritis; week; 150 without; radiographic progression ... See more keywords
THU0111 Novel autoantibody profiles in rheumatoid arthritis and their association with radiographic progression in the scottish early rheumatoid arthritis inception cohort and biobank (SERA)
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.2844
Abstract: Background Antibodies against citrullinated peptides are useful in the diagnosis of rheumatoid arthritis (RA) and are associated with poorer prognosis and greater radiographic progression. Novel autoantibodies recognising several post-translational modifications (PTM) are now emerging including… read more here.
Keywords: radiographic progression; rheumatoid arthritis; progression; carb ... See more keywords
AB1309 Radiographic progression of weight-bearing large joint damage in patients with rheumatoid arthritis during tnf-blocking therapies – maximum 12-year follow up –
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.1584
Abstract: Background We have demonstrated that TNF-blocking therapies are effective in inhibiting the radiographic progression in weight-bearing large joints with pre-existing Larsen grade 0-II during short term follow-up1,2). However, it is not clarified that the observed… read more here.
Keywords: weight bearing; year; radiographic progression; damage ... See more keywords