Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging
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DOI: 10.1021/acs.chemrev.1c00767
Abstract: The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical application in a rational manner depends on reliable, clinically applicable methods for determining the fate and trafficking of therapeutic cells in… read more here.
Keywords: cell tracking; cell; vivo cell; radiolabeling vivo ... See more keywords
Monitoring In Vivo Performances of Protein-Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00401
Abstract: In preclinical models, the development and optimization of protein-drug conjugates require accurate determination of the plasma and tissue profiles of both the protein and its conjugated drug. To this aim, we developed a bioanalytical strategy… read more here.
Keywords: drug conjugates; radiolabeling vivo; dual radiolabeling; drug ... See more keywords