Articles with "radioligand binding" as a keyword



Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies

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Published in 2017 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2016.11.016

Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Antagonists for ATP‐activated P2X4 ion channel receptors are currently in the focus as novel drug targets, in particular for the treatment of neuropathic and inflammatory pain. We stably… read more here.

Keywords: radioligand binding; p2x4 receptor; p2x4; binding studies ... See more keywords
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Rotenoids and Other Specialized Metabolites from the Roots of Mirabilis multiflora: Opioid and Cannabinoid Receptor Radioligand Binding Affinities.

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Published in 2021 at "Journal of natural products"

DOI: 10.1021/acs.jnatprod.0c00939

Abstract: Mirabilis multiflora is an acclaimed hallucinogen consumed traditionally by the Hopi Indians to induce diagnostic visions. Its root extract afforded a new (3) and four known (2, 5, 6, and 7) 12a-hydroxyrotenoids, a known rotenoid… read more here.

Keywords: radioligand binding; binding affinities; mirabilis multiflora; receptor ... See more keywords