Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome
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DOI: 10.1002/ana.26555
Abstract: The radiologically isolated syndrome (RIS) represents the earliest detectable pre‐clinical phase of multiple sclerosis (MS). This study evaluated the impact of therapeutic intervention in preventing first symptom manifestation at this stage in the disease spectrum. read more here.
Keywords: isolated syndrome; radiologically isolated; fumarate delays; multiple sclerosis ... See more keywords
Digital biomarkers can highlight subtle clinical differences in radiologically isolated syndrome compared to healthy controls
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DOI: 10.1007/s00415-020-10276-w
Abstract: To explore the use of digital biomarkers to distinguish healthy controls (HC) from subjects with a radiologically isolated syndrome (RIS). We developed a smartphone application called MS Screen Test (MSST) to explore several dimensions of… read more here.
Keywords: radiologically isolated; healthy controls; ris subjects; isolated syndrome ... See more keywords
Radiologically isolated syndrome in children: Current knowledge and future directions.
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DOI: 10.1016/j.msard.2018.06.010
Abstract: As the use of magnetic resonance imaging (MRI) grows in clinical practice, clinicians are increasingly faced with the difficult task of interpreting the significance of incidental findings on brain MRI. Among individuals found to have… read more here.
Keywords: radiologically isolated; syndrome children; current knowledge; isolated syndrome ... See more keywords
Assessing cognitive performance in radiologically isolated syndrome.
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DOI: 10.1016/j.msard.2019.04.030
Abstract: BACKGROUND Radiologically isolated syndrome (RIS) is defined as the occurrence of incidental brain MRI lesions suggestive of multiple sclerosis (MS) in otherwise healthy subjects without any signs or symptoms that could indicate to the disease.… read more here.
Keywords: radiologically isolated; age; cognitive performance; ris ... See more keywords
Inner retinal layer thinning in radiologically isolated syndrome predicts conversion to multiple sclerosis
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DOI: 10.1111/ene.14416
Abstract: Individuals with radiologically isolated syndrome (RIS) are at increased risk of converting to multiple sclerosis (MS). Early identification of later converters is crucial for optimal treatment decisions. The purpose of this study was to assess… read more here.
Keywords: radiologically isolated; inner retinal; conversion; isolated syndrome ... See more keywords
Should we treat pediatric radiologically isolated syndrome? An 18-year follow-up case report
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2023.1145260
Abstract: Background Radiologically isolated syndrome (RIS) describes asymptomatic individuals with incidental radiologic abnormalities suggestive of multiple sclerosis (MS). Much of RIS literature is about adult-onset cases. Treatment of RIS is controversial, especially in pediatric age, but… read more here.
Keywords: report; treat pediatric; isolated syndrome; case ... See more keywords
Advanced central nervous system imaging biomarkers in radiologically isolated syndrome: a mini review
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DOI: 10.3389/fneur.2023.1172807
Abstract: Radiologically isolated syndrome is characterised by central nervous system white-matter hyperintensities highly suggestive of multiple sclerosis in individuals without a neurological history of clinical demyelinating episodes. It probably represents the pre-symptomatic phase of clinical multiple… read more here.
Keywords: central nervous; mini review; isolated syndrome; radiologically isolated ... See more keywords