A Systematic Investigation into the Influence of Net Charge on the Biological Distribution of Radiometalated Peptides Using [68Ga]Ga-DOTA-TATE Derivatives.
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DOI: 10.1021/acs.bioconjchem.3c00007
Abstract: Recently, several radiometalated peptides have been approved for clinical imaging and/or therapy (theranostics) of several types of cancer; nonetheless, the primary challenge that most of these peptides confront is significant renal uptake and retention, which… read more here.
Keywords: net charge; tate; dota tate; 68ga dota ... See more keywords