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   Articles with "radioresistance" as a keyword



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Profiling of Tumor Cell‐Delivered Exosome by Surface Enhanced Raman Spectroscopy‐Based Biosensor for Evaluation of Nasopharyngeal Cancer Radioresistance

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recommendations! Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202202482

Abstract: Although the advancement of radiotherapy significantly improves the survival of nasopharyngeal cancer (NPC), radioresistance associated with recurrence and poor outcomes still remains a daunting challenge in the clinical scenario. Currently, effective biomarkers and convenient detection… read more here.

Keywords: spectroscopy; surface enhanced; nasopharyngeal cancer; raman spectroscopy ... See more keywords
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Fractionated radiotherapy might induce epithelial‐mesenchymal transition and radioresistance in a cellular context manner

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recommendations! Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28148

Abstract: Despite the fact that radiotherapy is a main therapeutic modality in cancer treatment, recent evidence suggests that fractionated radiotherapy (FR) might confer radioresistance through epithelial‐mesenchymal transition (EMT). Nevertheless, the effects of FR on EMT phenotype… read more here.

Keywords: mesenchymal transition; radioresistance; radiotherapy; radiotherapy might ... See more keywords
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Itraconazole attenuates the stemness of nasopharyngeal carcinoma cells via triggering ferroptosis

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recommendations! Published in 2020 at "Environmental Toxicology"

DOI: 10.1002/tox.23031

Abstract: Radiotherapy is a common therapy method for nasopharyngeal carcinoma (NPC) treatment; however, radioresistance greatly limits the clinical efficiency and prognosis of NPC patients. Therefore, it is extremely urgent to reveal the underlying mechanism contributing to… read more here.

Keywords: itraconazole; radioresistance; npc spheroids; ferroptosis ... See more keywords
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Radiotherapy resistance: identifying universal biomarkers for various human cancers

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recommendations! Published in 2022 at "Journal of Cancer Research and Clinical Oncology"

DOI: 10.1007/s00432-022-03923-4

Abstract: Radiotherapy (RT) is considered as a standard in the treatment of most solid cancers, including glioblastoma, lung, breast, rectal, prostate, colorectal, cervical, esophageal, and head and neck cancers. The main challenge in RT is tumor… read more here.

Keywords: biomarkers various; radiotherapy resistance; resistance identifying; universal biomarkers ... See more keywords
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DCLK1 as a Promising Marker for Radioresistance in Colorectal Cancer

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recommendations! Published in 2019 at "Journal of Gastrointestinal Cancer"

DOI: 10.1007/s12029-019-00292-z

Abstract: Colorectal cancer (CRC) is considered third in terms of frequency and second regarding of mortality, where it has been estimated, over 1.8 million new colorectal cancer cases and 881,000 deaths occurred in 2018 [1]. It… read more here.

Keywords: radioresistance; colorectal cancer; crc; cancer ... See more keywords
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Upregulated AHIF-mediated radioresistance in glioblastoma.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.12.136

Abstract: Long non-coding RNAs (lncRNAs) play vital roles in the pathobiology of glioblastoma multiforme (GBM). Though radiotherapy remains the most effective component of multiple therapies for patients with GBM, lncRNAs conferring GBM radioresistance are less unknown.… read more here.

Keywords: mediated radioresistance; ahif mediated; gbm; radioresistance ... See more keywords
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Polarization of tumor-associated macrophages by TLR7/8 conjugated radiosensitive peptide hydrogel for overcoming tumor radioresistance

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recommendations! Published in 2022 at "Bioactive Materials"

DOI: 10.1016/j.bioactmat.2021.12.033

Abstract: Radioresistance reduces the antitumor efficiency of radiotherapy and further restricts its clinical application, which is mainly caused by the aggravation of immunosuppressive tumor microenvironment (ITM). Especially tumor-associated macrophages (TAMs) usually display the tumor-promoting M2 phenotype… read more here.

Keywords: radioresistance; tlr7; tumor; tumor associated ... See more keywords
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HPV-induced Nurr1 promotes cancer aggressiveness, self-renewal, and radioresistance via ERK and AKT signaling in cervical cancer.

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recommendations! Published in 2020 at "Cancer letters"

DOI: 10.1016/j.canlet.2020.09.025

Abstract: Human papillomavirus (HPV) is the etiological agent of cervical cancer; however, the mechanisms underlying HPV-mediated carcinogenesis remain poorly understood. Here, we showed that nuclear receptor related-1 protein (Nurr1) was upregulated in primary cervical cancer tissue-derived… read more here.

Keywords: nurr1 promotes; cancer aggressiveness; radioresistance; cervical cancer ... See more keywords
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Breast cancer radioresistance may be overcome by osteopontin gene knocking out with CRISPR/Cas9 technique.

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recommendations! Published in 2021 at "Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique"

DOI: 10.1016/j.canrad.2020.08.048

Abstract: PURPOSE Osteopontin (OPN) is a phosphoglycoprotein, with a wide range of physiological and pathological roles. High expression of OPN promotes aggressive behavior, causes poor prognosis in tumor cells, and reduces the survival of patients. Since… read more here.

Keywords: crispr cas9; radioresistance; gene knocking; gene ... See more keywords
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Circ_0011058 facilitates proliferation, angiogenesis and radioresistance in papillary thyroid cancer cells by positively regulating YAP1 via acting as miR-335-5p sponge.

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recommendations! Published in 2021 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2021.110155

Abstract: BACKGROUND Circular RNAs (circRNAs) are reported to be associated with multiple biological processes in human cancers. However, there are still numerous circRNAs whose functions remain unclear. The aim of this study was to investigate the… read more here.

Keywords: circ 0011058; mir 335; radioresistance; proliferation angiogenesis ... See more keywords
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Targeted Proteomic Analysis of Small GTPases in Radioresistant Breast Cancer Cells.

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recommendations! Published in 2022 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.2c02389

Abstract: Radiation therapy benefits more than 50% of all cancer patients and cures 40% of them, where ionizing radiation (IR) deposits energy to cells and tissues, thereby eliciting DNA damage and resulting in cell death. Small… read more here.

Keywords: small gtpases; cancer; breast cancer; cancer cells ... See more keywords