The impact of radiosensitivity on clinical outcomes of spinal metastases treated with stereotactic body radiotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6019
Abstract: BACKGROUND To evaluate the impact of radiosensitivity on outcomes of spinal metastases treated with stereotactic body radiotherapy (SBRT) and identify the correlated prognostic factors. METHODS The authors retrospectively reviewed the records of all patients who… read more here.
Keywords: impact radiosensitivity; pain; spinal metastases; radiosensitivity ... See more keywords
The increased expression of cytokeratin 13 leads to an increase in radiosensitivity of nasopharyngeal carcinoma HNE-3 cells by upregulating ERRFI1.
Sign Up to like & getrecommendations! Published in 2023 at "IUBMB life"
DOI: 10.1002/iub.2724
Abstract: The main factors contributing to the unfavorable outcome in the clinical treatment of patients with nasopharyngeal carcinoma (NPC) patients are radiation resistance and recurrence. This study aimed to investigate the sensitivity and molecular foundation of… read more here.
Keywords: cell; apoptosis; hne; expression ... See more keywords
In Vitro Methods for the Study of Glioblastoma Stem-Like Cell Radiosensitivity.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1225-5_3
Abstract: Ionizing radiation is a critical component of glioblastoma (GBM) therapy. Recent data have implicated glioblastoma stem-like cells (GSCs) as determinants of GBM development, maintenance, and treatment response. Understanding the response of GSCs to radiation should… read more here.
Keywords: radiosensitivity; methods study; vitro methods; stem like ... See more keywords
Knockdown of SUMO1P3 represses tumor growth and invasion and enhances radiosensitivity in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-018-3379-8
Abstract: Hepatocellular carcinoma (HCC) is one of the most common types of malignant tumors with high recurrence and metastasis rates. Radiotherapy represents a major therapeutic option for HCC patients. However, the efficacy of radiotherapy has been… read more here.
Keywords: hepatocellular carcinoma; radiosensitivity; hcc; invasion ... See more keywords
Radiobiological Characterization of Tuberous Sclerosis: a Delay in the Nucleo-Shuttling of ATM May Be Responsible for Radiosensitivity
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0648-6
Abstract: The tuberous sclerosis complex (TSC) syndrome is associated with numerous cutaneous pathologies (notably on the face), epilepsy, intellectual disability and developmental retardation and, overall, high occurrence of benign tumors in several organs, like angiofibromas, giant… read more here.
Keywords: radiosensitivity; nucleo shuttling; tuberous sclerosis; delay ... See more keywords
Radiosensitivity enhancement of human thyroid carcinoma cells by the inhibitors of histone deacetylase sodium butyrate and valproic acid
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2018.08.007
Abstract: Radiotherapy is one of the leading treatments for clinical cancer therapy. External beam radiotherapy has been proposed as an adjuvant treatment for patients bearing differentiated thyroid cancer refractory to conventional therapy. Our purpose was to… read more here.
Keywords: human thyroid; radiosensitivity; thyroid cancer; thyroid ... See more keywords
Restored microRNA-519a enhances the radiosensitivity of non-small cell lung cancer via suppressing EphA2
Sign Up to like & getrecommendations! Published in 2021 at "Gene Therapy"
DOI: 10.1038/s41434-020-00213-x
Abstract: Accumulating evidence has demonstrated that microRNA-519a (miR-519a) acts as the tumor suppressor in various cancers, but little is known regarding its intrinsic regulatory mechanisms in non-small cell lung cancer (NSCLC). Here, we aimed to investigate… read more here.
Keywords: radiosensitivity; microrna 519a; mir 519a; epha2 ... See more keywords
Identification of non-invasive biomarkers for predicting the radiosensitivity of nasopharyngeal carcinoma from serum microRNAs
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-61958-4
Abstract: Serum microRNAs (miRNAs) have been reported as novel biomarkers for various diseases. But circulating biomarkers for predicting the radiosensitivity of nasopharyngeal carcinoma (NPC) have not been used in clinical practice. To screen out of differently… read more here.
Keywords: radiosensitivity; hsa mir; predicting radiosensitivity; serum ... See more keywords
MicroRNA-107 enhances radiosensitivity by suppressing granulin in PC-3 prostate cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71128-1
Abstract: Prostate cancer is the second leading cause of cancer-related death worldwide. Radiotherapy is often applied for the treatment, but radioresistance is a challenge in some patients. MicroRNAs have been reported to be involved in the… read more here.
Keywords: radiosensitivity; mir 107; prostate cancer; cancer ... See more keywords
Predicting chromosome damage in astronauts participating in international space station missions
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-84242-5
Abstract: Space radiation consists of energetic protons and other heavier ions. During the International Space Station program, chromosome aberrations in lymphocytes of astronauts have been analyzed to estimate received biological doses of space radiation. More specifically,… read more here.
Keywords: radiosensitivity; space; space radiation; flight ... See more keywords
Retracted Article: Circular RNA PTK2 modifies the progression and radiosensitivity in gastric cancer via miR-369-3p/ZEB1 axis
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/c9ra08525d
Abstract: Gastric cancer (GC) is one of the common cancers worldwide. Emerging findings imply that aberrant expression of circular RNA_0003221 (circPTK2) is involved in GC. Nevertheless, the function of circPTK2 in GC needs more explanation. Profiles… read more here.
Keywords: radiosensitivity; circptk2; gastric cancer; rna ... See more keywords