Octadecyl Gallate and Lipid‐Modified MnSe2 Nanoparticles Enhance Radiosensitivity in Esophageal Squamous Cell Carcinoma and Promote Radioprotection in Normal Tissues
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202311291
Abstract: Radiotherapy, a widely used therapeutic strategy for esophageal squamous cell carcinoma (ESCC), is always limited by radioresistance of tumor tissues and side‐effects on normal tissues. Herein, a signature based on four core genes of cyclic… read more here.
Keywords: normal tissues; esophageal squamous; radiosensitivity; squamous cell ... See more keywords
The impact of radiosensitivity on clinical outcomes of spinal metastases treated with stereotactic body radiotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6019
Abstract: BACKGROUND To evaluate the impact of radiosensitivity on outcomes of spinal metastases treated with stereotactic body radiotherapy (SBRT) and identify the correlated prognostic factors. METHODS The authors retrospectively reviewed the records of all patients who… read more here.
Keywords: impact radiosensitivity; pain; spinal metastases; radiosensitivity ... See more keywords
The increased expression of cytokeratin 13 leads to an increase in radiosensitivity of nasopharyngeal carcinoma HNE-3 cells by upregulating ERRFI1.
Sign Up to like & getrecommendations! Published in 2023 at "IUBMB life"
DOI: 10.1002/iub.2724
Abstract: The main factors contributing to the unfavorable outcome in the clinical treatment of patients with nasopharyngeal carcinoma (NPC) patients are radiation resistance and recurrence. This study aimed to investigate the sensitivity and molecular foundation of… read more here.
Keywords: cell; apoptosis; hne; expression ... See more keywords
Inhibition of Linc00284 Enhances Radiosensitivity in Colorectal Cancer Through miR‐559/c‐Myc Axis
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.70410
Abstract: Colorectal cancer (CRC), the most prevalent malignancy of the gastrointestinal tract, is commonly treated with radiotherapy; however, radioresistance often leads to poor prognosis. Long intergenic noncoding RNAs (LincRNAs), a subclass of long noncoding RNAs (lncRNAs),… read more here.
Keywords: colorectal cancer; 559 myc; crc; radiosensitivity ... See more keywords
In Vitro Methods for the Study of Glioblastoma Stem-Like Cell Radiosensitivity.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1225-5_3
Abstract: Ionizing radiation is a critical component of glioblastoma (GBM) therapy. Recent data have implicated glioblastoma stem-like cells (GSCs) as determinants of GBM development, maintenance, and treatment response. Understanding the response of GSCs to radiation should… read more here.
Keywords: radiosensitivity; methods study; vitro methods; stem like ... See more keywords
Knockdown of SUMO1P3 represses tumor growth and invasion and enhances radiosensitivity in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-018-3379-8
Abstract: Hepatocellular carcinoma (HCC) is one of the most common types of malignant tumors with high recurrence and metastasis rates. Radiotherapy represents a major therapeutic option for HCC patients. However, the efficacy of radiotherapy has been… read more here.
Keywords: hepatocellular carcinoma; radiosensitivity; hcc; invasion ... See more keywords
Radiobiological Characterization of Tuberous Sclerosis: a Delay in the Nucleo-Shuttling of ATM May Be Responsible for Radiosensitivity
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0648-6
Abstract: The tuberous sclerosis complex (TSC) syndrome is associated with numerous cutaneous pathologies (notably on the face), epilepsy, intellectual disability and developmental retardation and, overall, high occurrence of benign tumors in several organs, like angiofibromas, giant… read more here.
Keywords: radiosensitivity; nucleo shuttling; tuberous sclerosis; delay ... See more keywords
Radiosensitivity enhancement of human thyroid carcinoma cells by the inhibitors of histone deacetylase sodium butyrate and valproic acid
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2018.08.007
Abstract: Radiotherapy is one of the leading treatments for clinical cancer therapy. External beam radiotherapy has been proposed as an adjuvant treatment for patients bearing differentiated thyroid cancer refractory to conventional therapy. Our purpose was to… read more here.
Keywords: human thyroid; radiosensitivity; thyroid cancer; thyroid ... See more keywords
G9a deficiency activates TMEM27 to promote ferroptosis and enhances radiosensitivity in head and neck squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Cell Death Discovery"
DOI: 10.1038/s41420-025-02805-1
Abstract: Epigenetic regulation, which modulates gene expression without altering the DNA sequence, plays a critical role in adaptive responses to environmental stressors, including irradiation. In this study, we investigated the role of histone H3K9 methylation in… read more here.
Keywords: neck squamous; g9a; head neck; radiosensitivity ... See more keywords
Restored microRNA-519a enhances the radiosensitivity of non-small cell lung cancer via suppressing EphA2
Sign Up to like & getrecommendations! Published in 2021 at "Gene Therapy"
DOI: 10.1038/s41434-020-00213-x
Abstract: Accumulating evidence has demonstrated that microRNA-519a (miR-519a) acts as the tumor suppressor in various cancers, but little is known regarding its intrinsic regulatory mechanisms in non-small cell lung cancer (NSCLC). Here, we aimed to investigate… read more here.
Keywords: radiosensitivity; microrna 519a; mir 519a; epha2 ... See more keywords
Identification of non-invasive biomarkers for predicting the radiosensitivity of nasopharyngeal carcinoma from serum microRNAs
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-61958-4
Abstract: Serum microRNAs (miRNAs) have been reported as novel biomarkers for various diseases. But circulating biomarkers for predicting the radiosensitivity of nasopharyngeal carcinoma (NPC) have not been used in clinical practice. To screen out of differently… read more here.
Keywords: radiosensitivity; hsa mir; predicting radiosensitivity; serum ... See more keywords