111In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells† †Electronic supplementary information (ESI) available: Supplementary figures and tables. See DOI: 10.1039/c7nr09606b
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DOI: 10.1039/c7nr09606b
Abstract: EGFR-targeted PLGA nanoparticles co-deliver the Auger electron emitter 111In and a ruthenium(ii) radiosensitizer for combined therapeutic effects. read more here.
Keywords: ruthenium; polymeric nanoparticles; labelled polymeric; egfr targeted ... See more keywords
Abstract 5853: Peroxiredoxin I-targeted AMRI-59 has a role of radiosensitizer by promoting induction of ROS/γH2AX/caspase pathway and suppression of ERK
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DOI: 10.1158/1538-7445.am2017-5853
Abstract: We have identified AMRI-59, one of small molecule, is specific pharmaceutical inhibitor of peroxiredoxin (PRX) I enzyme activity in our previous study. In this study, we tried to prove whether AMRI-59 has role of radiosensitizer… read more here.
Keywords: suppression; amri role; role radiosensitizer; ros h2ax ... See more keywords
Abstract 6408: Anti-tumor immunity evolved by novel titanium peroxide nanoparticles (TiOxNPs) as a radiosensitizer and PD-1 blockade
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DOI: 10.1158/1538-7445.am2023-6408
Abstract: Abstract: Release and presentation of tumor antigens are the preconditions of cellular immune response. Radiotherapy have been reported to release endogenous tumor antigens and enhanced the adjuvanticity from dying cancer cells via endoplasmic reticulum (ER)… read more here.
Keywords: tumor immunity; anti tumor; tumor antigens; radiosensitizer ... See more keywords
JNC-1043, a Novel Podophyllotoxin Derivative, Exerts Anticancer Drug and Radiosensitizer Effects in Colorectal Cancer Cells
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DOI: 10.3390/molecules27207008
Abstract: The objective of this study was to determine whether (5S)-5-(4-benzyloxy-3,5-dimethoxy-phenyl)-5,9-dihydro-8H-furo [3’,4’:6,7] naphtho [2,3-d] [1,3]dioxol-6-one (JNC-1043), which is a novel chemical derivative of β-apopicropodophyllin, acts as a novel potential anticancer reagent and radiosensitizer in colorectal cancer… read more here.
Keywords: cell death; jnc 1043; jnc; combination jnc ... See more keywords