Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity.
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DOI: 10.1016/j.ejmech.2020.112449
Abstract: In the present work, we report the design and synthesis of a set of iodinated quinazolinones carrying benzenesulfonamide moiety as carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. The target compounds showed promising inhibitory activity against the… read more here.
Keywords: carbonic anhydrase; radiosensitizing activity; xii; hca ... See more keywords