Radiotherapy, Temozolomide, and Antiprogrammed Cell Death Protein 1 Treatments Modulate the Immune Microenvironment in Experimental High-Grade Glioma.
Sign Up to like & getrecommendations! Published in 2020 at "Neurosurgery"
DOI: 10.1093/neuros/nyaa421
Abstract: BACKGROUND The lack of immune synergy with conventional chemoradiation could explain the failure of checkpoint inhibitors in current clinical trials for high-grade gliomas (HGGs). OBJECTIVE To analyze the impact of radiotherapy (RT), Temozolomide (TMZ) and… read more here.
Keywords: high grade; radiotherapy temozolomide; immune microenvironment; tmz ... See more keywords
Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology letters"
DOI: 10.3892/ol.2017.6251
Abstract: In previous trials, bevacizumab failed to prolong the overall survival time in newly diagnosed glioblastoma and at the first recurrence. Randomized clinical trials at the second or further recurrence following the failure of radiotherapy, temozolomide… read more here.
Keywords: response; treatment; radiotherapy temozolomide; temozolomide lomustine ... See more keywords