α‐Synuclein Radiotracer Development and In Vivo Imaging: Recent Advancements and New Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.28984
Abstract: α‐Synucleinopathies including idiopathic Parkinson's disease, dementia with Lewy bodies and multiple systems atrophy share overlapping symptoms and pathological hallmarks. Selective neurodegeneration and Lewy pathology are the main hallmarks of α‐synucleinopathies. Currently, there is no imaging… read more here.
Keywords: lewy pathology; development; pathology; aggregated syn ... See more keywords
Computational Chemistry for the Identification of Lead Compounds for Radiotracer Development
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16020317
Abstract: The use of computer-aided drug design (CADD) for the identification of lead compounds in radiotracer development is steadily increasing. Traditional CADD methods, such as structure-based and ligand-based virtual screening and optimization, have been successfully utilized… read more here.
Keywords: virtual screening; chemistry; compounds radiotracer; radiotracer development ... See more keywords