Identification of Radix bupleuri from different geographic origins using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and support vector machine algorithm.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsad060
Abstract: BACKGROUND The geographic origin of Radix bupleuri is an important factor affecting its efficacy, which needs to be effectively identified. OBJECTIVE The goal is to enrich and develop the intelligent recognition technology applicable to the… read more here.
Keywords: radix bupleuri; identification; origin; matrix assisted ... See more keywords
Clerosterol from vinegar-baked radix bupleuri modifies drug transport
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DOI: 10.18632/oncotarget.15212
Abstract: Vinegar-baked Radix Bupleuri (VBRB) is reportedly used to treat liver cancer when combined with traditional chemotherapy and data show that this combination may modify drug transport. We isolated clerosterol from VBRB and studied its effect… read more here.
Keywords: clerosterol; baked radix; drug; radix bupleuri ... See more keywords
Therapeutic effects of total saikosaponins from Radix bupleuri against Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.940999
Abstract: Alzheimer’s disease (AD) is a neurodegenerative disease characterized by memory loss and cognitive dysfunction in the elderly, with amyloid-beta (Aβ) deposition and hyperphosphorylation of tau protein as the main pathological feature. Nuclear factor 2 (Nrf2)… read more here.
Keywords: radix bupleuri; disease; alzheimer disease; bace1 ... See more keywords
Assessment of Genetic Diversity in Bupleurum spp. Basing Agronomic Traits, Medicinal Components and ISSR Markers
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DOI: 10.3390/genes14040951
Abstract: Radix bupleuri is one of the bulk medicinal materials in China and it is widely adopted in clinical applications and drug discovery. The investigation of agronomic traits, active component content and genetic diversity in diverse… read more here.
Keywords: radix bupleuri; agronomic traits; genetic diversity; content ... See more keywords
Quantitative Analysis and Differential Evaluation of Radix Bupleuri Cultivated in Different Regions Based on HPLC-MS and GC-MS Combined with Multivariate Statistical Analysis
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DOI: 10.3390/molecules27154830
Abstract: The quality of Radix Bupleuri is greatly affected by its growing environment. In this study, Radix Bupleuri samples that were harvested from seven different regions across northwest China were examined by high-performance liquid chromatography (HPLC)… read more here.
Keywords: radix bupleuri; bupleuri; bupleuri samples; analysis ... See more keywords