Articles with "radix rubra" as a keyword



Effects of Paeoniae Radix Rubra on lowering lipid via bioinformatics and gut microbiome

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-08486-1

Abstract: Hyperlipidemia, a metabolic disorder characterized by abnormal lipid levels, is closely linked to an increased risk of cardiovascular disease. In this study, we investigated the hypolipidemic properties of Paeoniae Radix Rubra and its regulatory effects… read more here.

Keywords: rubra lowering; radix rubra; effects paeoniae; paeoniae radix ... See more keywords

First Report of Root Rot caused by Coniella fragariae on Paeoniae radix Rubra in China.

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Published in 2023 at "Plant disease"

DOI: 10.1094/pdis-12-22-2773-pdn

Abstract: Paeoniae radix Rubra is a traditional Chinese herbal medicine, which has the effect of clearing heat and cooling blood, activating blood and removing stasis. It has become popular in the Chinese market in recent years… read more here.

Keywords: root; radix rubra; root rot; root segments ... See more keywords

The therapeutic effects of Paeoniae Radix Rubra on chronic hepatitis through network pharmacology and molecular docking

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Published in 2024 at "Medicine"

DOI: 10.1097/md.0000000000040796

Abstract: Backgrounds: Chronic hepatitis (CH) refers to liver inflammation lasting at least 6 months caused by various factors, significantly impacting patients’ daily lives. Paeoniae Radix Rubra (CS) is a classic blood-activating and stasis-dissolving herb known for… read more here.

Keywords: molecular docking; radix rubra; paeoniae radix; pharmacology ... See more keywords

Effect of Paeoniae Radix Rubra (Paeonia lactiflora Pall.) extract on mucin secretion, gene expression in human airway epithelial cells.

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Published in 2022 at "Journal of ethnopharmacology"

DOI: 10.2139/ssrn.4195314

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Paeoniae Radix Rubra (PRR), the root of Paeonia lactiflora Pall., is a traditional Chinese medicine which has the effects of regulating various inflammatory diseases, treating blood stasis, and enhancing blood circulation. AIM OF… read more here.

Keywords: paeoniae radix; radix rubra; gene expression; expression ... See more keywords

Investigation into the Mechanisms of Paeoniae Radix Rubra in the Treatment of Venous Thrombosis Using Network Pharmacology, Bioinformatics, and Molecular Docking Techniques.

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Published in 2025 at "Current pharmaceutical design"

DOI: 10.2174/0113816128374345250521115849

Abstract: OBJECTIVE This study investigates the potential targets and mechanisms of Paeoniae Radix Rubra (PRR) in treating Venous Thrombosis (VTE) by employing network pharmacology, bioinformatics analysis, and molecular docking validation. METHODS Active components of PRR were… read more here.

Keywords: molecular docking; mechanisms paeoniae; radix rubra; paeoniae radix ... See more keywords

Metabolism of Paeoniae Radix Rubra and its 14 constituents in mice

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.995641

Abstract: Objective: Paeoniae Radix Rubra (PRR) is a commonly used traditional Chinese medicine with the effects of clearing away heat, cooling the blood, and relieving blood stasis. To 1) elucidate the metabolites and metabolic pathways of… read more here.

Keywords: paeoniae radix; constituents mice; radix rubra;

Chishao (Paeoniae Radix Rubra) alleviates intra-hepatic cholestasis by modulating NTCP in rats

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Published in 2024 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2024.1341651

Abstract: Background: Cholestasis is a common pathological manifestation dominated by accumulation of potentially toxic biliary compounds. Na+-taurocholate cotransporting polypeptide (NTCP) plays a critical role in protection from cholestasis and can be targeted therapeutically. Chishao (Paeoniae Radix… read more here.

Keywords: radix rubra; expression ntcp; paeoniae radix; cholestasis ... See more keywords