Articles with "radotinib hcl" as a keyword



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The c-Abl inhibitor, Radotinib HCl, is neuroprotective in a preclinical Parkinson’s disease mouse model

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Published in 2018 at "Human Molecular Genetics"

DOI: 10.1093/hmg/ddy143

Abstract: Abstract Accumulating evidence suggests that the non-receptor tyrosine kinase c-Abl plays an important role in the progression of Parkinson’s disease (PD) and c-Abl inhibition could be neuroprotective in PD and related α-synucleinopathies. Nilotinib, a c-Abl… read more here.

Keywords: radotinib hcl; parkinson disease; abl inhibitor; radotinib ... See more keywords