Right Atrial Function Predicts Clinical Outcome in Patients with Precapillary Pulmonary Hypertension
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Society of Echocardiography"
DOI: 10.1016/j.echo.2018.05.015
Abstract: Background: Although the primary role of right atrial (RA) size in the diagnosis and risk stratification of precapillary pulmonary hypertension (PH) has been studied, little is known about the clinical significance of RA function. In… read more here.
Keywords: pulmonary hypertension; patients precapillary; right atrial; rafi ... See more keywords
RAF inhibitors activate the integrated stress response by direct activation of GCN2
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DOI: 10.1038/s41467-025-65376-w
Abstract: Paradoxical activation of wild type RAF by chemical RAF inhibitors (RAFi) is a well-understood ‘on-target’ biological and clinical response. In this study, we show that a range of RAFi drive ERK1/2-independent activation of the Unfolded… read more here.
Keywords: rafi; response; activation; gcn2 ... See more keywords