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Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental Therapeutics

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232214392

Abstract: Reliable preclinical models are needed for screening new cancer drugs. Thus, we developed an improved 3D tumor organoid model termed “organoid raft cultures” (ORCs). Development of ORCs involved culturing tumors ex vivo on collagen beds… read more here.

Keywords: abt 263; derived xenografts; patient derived; organoid raft ... See more keywords