The lipid raft-dwelling protein US9 can be manipulated to target APP compartmentalization, APP processing, and neurodegenerative disease pathogenesis
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DOI: 10.1038/s41598-017-15128-8
Abstract: The trafficking behavior of the lipid raft-dwelling US9 protein from Herpes Simplex Virus strikingly overlaps with that of the amyloid precursor protein (APP). Both US9 and APP processing machinery rely on their ability to shuttle… read more here.
Keywords: protein; neurodegenerative disease; app processing; raft dwelling ... See more keywords