Oral raft forming in situ gelling system for site specific delivery of calcium
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102113
Abstract: Abstract In situ gelling Raft forming system (GRFS), a novel sol-gel system of calcium carbonate (CC) was developed with the aim to prolong the gastric residence time and thereby the bioavailability. A simple lattice mixture… read more here.
Keywords: calcium; raft forming; system; situ gelling ... See more keywords
Formulation, optimization, and evaluation of raft-forming formulations containing Nizatidine
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2019.1569033
Abstract: Abstract Objective: The main objective of this research is to formulate, optimize, and evaluate raft-forming chewable tablets of Nizatidine. Various raft-forming agents were used in preliminary screening. Sodium alginate showed maximum raft strength, so tablets… read more here.
Keywords: raft forming; raft; drug; formulation optimization ... See more keywords
Characterization of raft-forming alginate suspensions formed in HCl or model food systems at varying pH levels to better simulate gastric postprandial conditions.
Sign Up to like & getrecommendations! Published in 2021 at "Drug development and industrial pharmacy"
DOI: 10.1080/03639045.2021.1954940
Abstract: OBJECTIVE Elucidate properties of raft-forming alginates in vitro with varying composition, system in which the raft was formed (HCl solution; tomato soup; protein-rich beverage), and pH levels for a more accurate representation of postprandial gastric… read more here.
Keywords: rafts formed; raft forming; formed hcl; hcl solution ... See more keywords