Development of RAG2 -/- IL2Rγ -/Y immune deficient FAH-knockout miniature pig
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.950194
Abstract: Human hepatocyte transplantation for liver disease treatment have been hampered by the lack of quality human hepatocytes. Pigs with their large body size, longevity and physiological similarities with human are appropriate animal models for the… read more here.
Keywords: rag2 il2r; human hepatocytes; rgfko pigs; development ... See more keywords
Expermental study on hepatic ischemia and reperfusion injury in Rag1 and Rag2/IL2rγ knockout mice
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Surgery"
DOI: 10.3760/cma.j.issn.1673-4203.2018.02.010
Abstract: Objective To explore the effect of lymphocytes on the innate immune cells in Rag1 and Rag2/IL2rγ gene knockout mice after hepatic ischemia and reperfusion injury (HIRI). Methods C57BL/6 mice(n=10), Rag1 knockout mice (n=10) and Rag2/IL2rγ… read more here.
Keywords: reperfusion injury; knockout mice; mice; rag2 il2r ... See more keywords