Anti-RAGE antibody attenuates isoflurane-induced cognitive dysfunction in aged rats
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DOI: 10.1016/j.bbr.2017.01.012
Abstract: HighlightsIsoflurane exposure induced impairment of hippocampus‐dependent spatial learning and memory in aged rats.RAGE antibody administration improve the BBB disruption, reduce the neuroinflamation and A&bgr; deposition.RAGE antibody administration attenuated the cognitive impairment induced by isoflurane exposure.… read more here.
Keywords: aged rats; exposure; rage; isoflurane ... See more keywords
Therapeutic Effectiveness of Anti-RAGE Antibody Administration in a Rat Model of Crush Injury
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DOI: 10.1038/s41598-017-12065-4
Abstract: Crush injury patients often have systemic inflammatory response syndrome that leads to multiple organ failure. Receptor for advanced glycation endproducts (RAGE) functions as a pattern recognition receptor that regulates inflammation. We evaluated the effects of… read more here.
Keywords: crush injury; anti rage; rage; rage antibody ... See more keywords