Inhibitory effects of RAGE-aptamer on development of monocrotaline-induced pulmonary arterial hypertension in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cardiology"
DOI: 10.1016/j.jjcc.2020.12.009
Abstract: BACKGROUND The receptor for advanced glycation end products (RAGE), a transmembrane receptor belonging to the immunoglobulin superfamily, is overexpressed in pulmonary artery smooth muscle cells (PASMCs) in patients with pulmonary arterial hypertension (PAH) and is… read more here.
Keywords: continuous subcutaneous; monocrotaline induced; rage aptamer; aptamer ... See more keywords
RAGE-aptamer Attenuates the Growth and Liver Metastasis of Malignant Melanoma in Nude Mice
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Medicine"
DOI: 10.2119/molmed.2017.00099
Abstract: Epidemiological studies have suggested a link between cumulative diabetic exposure and cancer. The interaction of advanced glycation end products (AGEs) with their receptor (RAGE) may contribute to the phenomenon. We examined the effects of DNA… read more here.
Keywords: melanoma; rage aptamer; nude mice; rage ... See more keywords