The RAGE/DIAPH1 axis: mediator of obesity and proposed biomarker of human cardiometabolic disease.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular research"
DOI: 10.1093/cvr/cvac175
Abstract: Overweight and obesity are leading causes of cardiometabolic dysfunction. Despite extensive investigation, the mechanisms mediating the increase in these conditions are yet to be fully understood. Beyond endogenous formation of advanced glycation end products (AGEs)… read more here.
Keywords: overweight obesity; rage; axis mediator; diaph1 axis ... See more keywords
New insights into RAGE/Diaph1 interaction as a modulator of actin cytoskeleton dynamics in peripheral nervous system in long‐term hyperglycaemia
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DOI: 10.1111/ejn.15991
Abstract: This review focuses on receptor for advanced glycation endproducts/diaphonous related formin 1 (RAGE/Diaph1) interaction as a modulator of actin cytoskeleton dynamics in peripheral nervous system (PNS) in diabetes. Deciphering the complex molecular interactions between RAGE… read more here.
Keywords: interaction modulator; actin cytoskeleton; modulator actin; rage ... See more keywords
The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications
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DOI: 10.3390/ijms23094579
Abstract: Increasing evidence links the RAGE (receptor for advanced glycation end products)/DIAPH1 (Diaphanous 1) signaling axis to the pathogenesis of diabetic complications. RAGE is a multi-ligand receptor and through these ligand–receptor interactions, extensive maladaptive effects are… read more here.
Keywords: diaph1 signaling; pathogenesis diabetic; diabetic complications; complications rage ... See more keywords