Abstract 3736: Role of RAI2 protein in progression of breast and prostate cancer to hormone independent disease
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-3736
Abstract: In breast cancer, low retinoic acid-2 (RAI2) gene expression is correlated with presence of disseminated tumor cells in the bone marrow of early stage patients and with poor outcome. Furthermore, the RAI2 protein acts as… read more here.
Keywords: hormone; breast; prostate cancer; cancer ... See more keywords
Abstract 3724: RAI2 controls polycomb-mediated repression of CDKN1A by its interaction with CtBP1
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DOI: 10.1158/1538-7445.am2023-3724
Abstract: RAI2 has initially been identified as a metastasis-associated gene in breast cancer. Recently, we found that increased RAI2 protein in primary tumors predicts early biochemical relapse of prostate cancer patients. On the molecular level, RAI2… read more here.
Keywords: interaction; cdkn1a; rai2; ctbp1 ... See more keywords
Abstract 3023: Master corepressor inactivation through oncogene suppressor RAI2 mediated polymerization
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DOI: 10.1158/1538-7445.am2024-3023
Abstract: Imbalanced transcription of a large number of genes can be caused at various levels, ranging from alterations in individual transcription factors to dysfunctional corepressor and coactivator complexes [1]. C-terminal binding proteins (CtBPs) are ubiquitous master… read more here.
Keywords: cancer; rai2; corepressor; polymerization ... See more keywords
Retinoic Acid-Induced 2 (RAI2) Is a Novel Antagonist of Wnt/β-Catenin Signaling Pathway and Potential Biomarker of Chemosensitivity in Colorectal Cancer
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DOI: 10.3389/fonc.2022.805290
Abstract: Objective Aberrant activation of Wnt/β-catenin signaling contributes to the maintenance of cancer stem cells and chemoresistance in colorectal cancer (CRC). Retinoic acid-induced 2 (RAI2) was proved to be a tumor suppressor in CRC in our… read more here.
Keywords: rai2; chemosensitivity; crc; ctbp2 ... See more keywords
Comprehensive analysis of the expression and prognosis for RAI2: A promising biomarker in breast cancer
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DOI: 10.3389/fonc.2023.1134149
Abstract: Introduction Retinoic acid-induced 2 (RAI2) was initially related to cell differentiation and induced by retinoic acid. RAI2 has been identified as an emerging tumor suppressor in breast cancer and colorectal cancer. Methods In this study,… read more here.
Keywords: rai2; expression; breast cancer; analysis ... See more keywords