TERT promoter mutation in primary papillary thyroid carcinoma lesions predicts absent or lower 131i uptake in metastases
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DOI: 10.1002/iub.2056
Abstract: Genetic mutations play important roles in not only development of papillary thyroid carcinoma (PTC) but also determination of its properties. The radioactive iodine refractory (RAIR) state is a harbinger of poor outcomes for PTC. We… read more here.
Keywords: papillary thyroid; group; rair; tert mutation ... See more keywords
Clinico-pathological factors associated with radioiodine refractory differentiated thyroid carcinoma status
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DOI: 10.1007/s40618-024-02352-z
Abstract: Risk factors for developing radioiodine refractory thyroid cancer (RAIR-TC) have rarely been analyzed. The purpose of the present study was to find clinical and pathological features associated with the occurrence of RAIR-disease in differentiated thyroid… read more here.
Keywords: rair; differentiated thyroid; refractory; radioiodine refractory ... See more keywords
Metabolomic screening of radioiodine refractory thyroid cancer patients and the underlying chemical mechanism of iodine resistance
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DOI: 10.1038/s41598-024-61067-6
Abstract: Radioiodine refractory (RAIR) patients do not benefit from iodine-131 therapy. Thus, timely identification of RAIR patients is critical for avoiding ineffective radioactive iodine therapy. In addition, determining the causes of iodine resistance will facilitate the… read more here.
Keywords: radioiodine refractory; rair; iodine resistance;
Can 99Tcm-3PRGD2(ανβ3) and 18F-FDG dual-tracer molecular imaging change the therapeutic strategy for progressive refractory differentiated thyroid cancer: Case report
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DOI: 10.1097/md.0000000000032751
Abstract: Rationale: The management of radioiodine refractory differentiated thyroid cancer (RAIR-DTC) represents a major challenge in thyroid cancer. The American Thyroid Association guidelines recommend the use of tyrosine kinase inhibitors (TKIs) for RAIR-DTC that does not… read more here.
Keywords: 99tcm 3prgd2; refractory differentiated; rair; thyroid cancer ... See more keywords
Survival outcomes in radioactive iodine-refractory (RAIR) differentiated thyroid cancer (DTC) with BRAF mutation: A real-world study from the Spanish Taskforce for Neuroendocrine and Endocrine Tumors (GETNE) Thyroid Cancer registry.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.e18159
Abstract: e18159 Background: For BRAF V600E RAIR-DTC, the role of BRAF with or without MEK inhibitors (BRAFi; MEKi) has been studied, given the success of these therapies in other solid tumors. Although BRAFi + MEKi are… read more here.
Keywords: rair; braf; survival; thyroid cancer ... See more keywords
A user-friendly nomogram for predicting radioiodine refractory differentiated thyroid cancer
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DOI: 10.3389/fendo.2023.1109439
Abstract: Background The diagnosis of radioiodine refractory differentiated thyroid cancer (RAIR-DTC) is primarily based on clinical evolution and iodine uptake over the lesions, which is still time-consuming, thus urging a predictive model for timely RAIR-DTC informing.… read more here.
Keywords: refractory differentiated; rair; differentiated thyroid; radioiodine refractory ... See more keywords
Current status of the prediction for radio-iodine refractory thyroid cancer: a narrative review
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2024.1433553
Abstract: It is well established that patients with the most differentiated thyroid cancers have a good prognosis, whereas when the disease develops into radio-iodine refractory thyroid cancer (RAIR) their prognosis is poor and the 10-year survival… read more here.
Keywords: rair; radio iodine; refractory thyroid; iodine refractory ... See more keywords
Clinical Characteristics of Adult Functional Constipation Patients with Rectoanal Areflexia and Their Response to Biofeedback Therapy
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DOI: 10.3390/diagnostics13020255
Abstract: Background: The London Classification for anorectal physiological dysfunction specifically proposes rectoanal areflexia (RA), which means the absence of a rectoanal inhibitory reflex (RAIR) based on a manometric diagnosis. Although RA is not observed in healthy… read more here.
Keywords: rectoanal areflexia; rair; adult patients; functional constipation ... See more keywords
Identification of Circulating Exosomal microRNAs Associated with Radioiodine Refractory in Papillary Thyroid Carcinoma
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DOI: 10.3390/jpm12122017
Abstract: Papillary thyroid carcinoma (PTC) has a favorable prognosis, but a fraction of cases show progressive behaviors, becoming radioiodine refractory (RAIR) PTC. To explore circulating exosomal microRNAs (miRNAs) associated with RAIR PTC, the miRNA profiles in… read more here.
Keywords: thyroid carcinoma; rair; rair ptc; circulating exosomal ... See more keywords
Differences in rectoanal inhibitory reflex duration between patients with refractory functional constipationand myelomeningocele.
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DOI: 10.5546/aap.2022-02598.eng
Abstract: Introduction. Usually, during anorectal manometry, only the presence or absence of rectoanal inhibitory reflex (RAIR) is investigated. Studies have reported that a detailed analysis may provide data of interest. Our hypothesis is that RAIR measurement… read more here.
Keywords: rair; rair duration; myelomeningocele; inhibitory reflex ... See more keywords