Toward predictive biomarkers of response to kinase inhibitor therapies in differentiated thyroid cancer
Sign Up to like & getrecommendations! Published in 2017 at "Endocrine"
DOI: 10.1007/s12020-017-1342-1
Abstract: Small-molecule kinase inhibitors have emerged as effective therapies for patients suffering from progressive, metastatic, radioiodine-refractory (RAIR) differentiated thyroid cancer (DTC) [1]. Sorafenib and lenvatinib are now subject to regulatory approval in the United States and… read more here.
Keywords: response; kinase; differentiated thyroid; thyroid cancer ... See more keywords
Impact of age on survival in radioiodine refractory differentiated thyroid cancer patients.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of endocrinology"
DOI: 10.1530/eje-20-1073
Abstract: OBJECTIVE The objectives of our study were to analyze the influence of age on the survival of patients with RAIR-DTC and to determine their prognostic factors according to age. METHODS This single centre, retrospective study… read more here.
Keywords: years old; age survival; impact age; age ... See more keywords
Feasibility of Apatinib in Radioiodine-Refractory Differentiated Thyroid Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.768028
Abstract: Objectives Our aim was to describe our experience in using apatinib as treatment for radioiodine-refractory differentiated thyroid carcinoma (RAIR-DTC). Methods Forty-seven patients undergoing apatinib treatment for RAIR-DTC were prospectively enrolled in this study. The study… read more here.
Keywords: thyroid carcinoma; differentiated thyroid; refractory differentiated; radioiodine refractory ... See more keywords
Theranostic Options for Radioiodine-Refractory Differentiated Thyroid Carcinoma: Recent Advances, Challenges, and Road Ahead
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DOI: 10.3389/fendo.2022.924841
Abstract: Radioiodine-refractory differentiated thyroid cancer (RAIR-DTC), though uncommon, presents a considerable therapeutic challenge with poor long-term outcomes. Currently, tyrosine kinase inhibitors are the mainstay of treatment for advanced RAIR-DTC patients. However, these agents are associated with… read more here.
Keywords: rair dtc; refractory differentiated; differentiated thyroid; radioiodine refractory ... See more keywords
Predictive Value of Clinical and Pathological Characteristics for Metastatic Radioactive Iodine-Refractory Differentiated Thyroid Carcinoma: A 16-year Retrospective Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.930180
Abstract: Purpose To assess predictive value of clinical and pathological characteristics for metastatic radioactive iodine-refractory differentiated thyroid carcinoma (RAIR-DTC) in early stage retrospectively. Methods We studied 199 metastatic DTC patients who were divided into two groups… read more here.
Keywords: rair dtc; tg1; sup; tg2 ... See more keywords