A specific inhibitor of polo-like kinase 1, GSK461364A, suppresses proliferation of Raji Burkitt's lymphoma cells through mediating cell cycle arrest, DNA damage, and apoptosis.
Sign Up to like & getrecommendations! Published in 2020 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2020.109288
Abstract: Polo-like kinase 1 (PLK1) is a prominent mediatory player during the cell cycle, mitosis, and cytokinesis in eukaryotic cells. Besides its physiological roles, PLK1 expression is upregulated in a wide range of human malignant tumors… read more here.
Keywords: raji; cycle arrest; gsk461364a; cell cycle ... See more keywords
PAX5 haploinsufficiency induce cancer cell dormancy in Raji cells
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DOI: 10.1016/j.yexcr.2018.02.010
Abstract: ABSTRACT PAX5 mutations have important role in leukemogenesis and leukemia relapse, cancer cell dormancy participates in cancer relapse, but there was no report about PAX5 mutation inducing cancer cell dormancy. we constructed the PAX5 deletion… read more here.
Keywords: raji; cell; cell dormancy; cancer cell ... See more keywords
The protective effects of antigen-specific IgY on pyocyanin-treated human lymphoma Raji cells.
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DOI: 10.12688/f1000research.19327.1
Abstract: Background: Pyocyanin (PCN), a highly pathogenic pigment produced by Pseudomonas aeruginosa, induces caspase 3-dependent human B cell (Raji cells) death. The aim of the present study, therefore, was to assess whether antigen-specific IgY antibodies may… read more here.
Keywords: raji; specific igy; antigen specific; raji cells ... See more keywords
Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1-DNMT3A-∆Np73 pathways
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DOI: 10.3892/mmr.2017.7423
Abstract: Emodin is an active constituent found in the roots and rhizomes of numerous Chinese medicinal herbs. It exerts antitumor activity against Dalton's lymphoma in vivo, although the detailed mechanisms by which emodin induces apoptosis remains… read more here.
Keywords: raji; lymphoma raji; raji cell; raji cells ... See more keywords