Articles with "ram2061" as a keyword



In Vivo Evaluation of Novel Geranylgeranyl Diphosphate Synthase Inhibitors

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Published in 2018 at "Blood"

DOI: 10.1182/blood-2018-99-113007

Abstract: The enzyme geranylgeranyl diphosphate synthase (GGDPS) synthesizes the 20-carbon isoprenoid geranylgeranyl diphosphate which is used in protein geranylgeranylation reactions. Our work has demonstrated that GGDPS inhibitors (GGDPSIs) represent a novel therapeutic strategy for multiple myeloma… read more here.

Keywords: ram2061; geranylgeranyl diphosphate; ram2061 ram2093; geranylgeranylation ... See more keywords