Purification and cDNA Cloning of Antimicrobial Peptides from the Skin Secretion of the Chinese Frog Rana chensinensis
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-020-10074-y
Abstract: The skin secretions of amphibians are a rich source of bioactive peptides. We isolated chensirin-1 and chensirin-2 from the skin secretion of the Chinese frog Rana chensinensis . Sephadex-G-50 and RP-HPLC were employed to purify… read more here.
Keywords: secretion chinese; rana chensinensis; frog rana; chinese frog ... See more keywords
Oxidative stress and hepatotoxicity of Rana chensinensis exposed to low doses of octylphenol.
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DOI: 10.1016/j.etap.2018.09.011
Abstract: This study investigated the effects of low doses of octylphenol (OP) on the oxidative stress and hepatotoxicity in amphibian liver. The frog, Rana chensinensis, were exposed to 10-8, 10-7, 10-6 mol/L OP for 10, 20… read more here.
Keywords: low doses; rana chensinensis; doses octylphenol; stress hepatotoxicity ... See more keywords
In Vitro & In Vivo Studies on Identifying and Designing Temporin-1CEh from the Skin Secretion of Rana chensinensis as the Optimised Antibacterial Prototype Drug
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DOI: 10.3390/pharmaceutics14030604
Abstract: Amphibian skin secretion is an ideal source of antimicrobial peptides that are difficult to induce drug resistance to due to their membrane-targeting mechanism as a new treatment scheme. In this study, a natural antimicrobial peptide… read more here.
Keywords: vitro vivo; rana chensinensis; temporin 1ceh; activity ... See more keywords