Articles with "ranbp2" as a keyword



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RanBP2 regulates the anti-retroviral activity of TRIM5α by SUMOylation at a predicted phosphorylated SUMOylation motif

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Published in 2018 at "Communications Biology"

DOI: 10.1038/s42003-018-0198-0

Abstract: TRIM5α is a cytoplasmic restriction factor that blocks post-entry retroviral infection. Evidence suggests that its antiviral activity can be regulated by SUMO, but how this is achieved remains unknown. Here, we show that TRIM5α forms… read more here.

Keywords: sumoylation; ranbp2; antiviral activity; trim5 ... See more keywords
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Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes

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Published in 2017 at "Cell Cycle"

DOI: 10.1080/15384101.2017.1339847

Abstract: ABSTRACT In previous studies, we observed that Zeta-chain-associated protein kinase 70 (Zap70) regulates spindle assembly and chromosome alignment in mouse oocyte and that Ran binding protein 2 (RanBP2) is a highly associated gene with Zap70… read more here.

Keywords: ranbp2; cell cycle; exact timing; zap70 ... See more keywords
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Relapsing necrotising encephalomyelopathy due to RANBP2 mutation

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Published in 2019 at "Practical Neurology"

DOI: 10.1136/practneurol-2018-002063

Abstract: A young woman with a history of previously undiagnosed episodic neurological deterioration since early childhood associated with viral illnesses developed fulminant encephalitis. Standard investigations gave no diagnosis. Next-generation sequencing identified a heterozygous mutation c.1754C>T (p.Thr585Met)… read more here.

Keywords: ranbp2; relapsing necrotising; encephalomyelopathy due; necrotising encephalomyelopathy ... See more keywords
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RANBP2 and USP9x regulate nuclear import of adenovirus minor coat protein IIIa

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Published in 2022 at "PLoS Pathogens"

DOI: 10.1371/journal.ppat.1010588

Abstract: As intracellular parasites, viruses exploit cellular proteins at every stage of infection. Adenovirus outbreaks are associated with severe acute respiratory illnesses and conjunctivitis, with no specific antiviral therapy available. An adenoviral vaccine based on human… read more here.

Keywords: ranbp2; nuclear import; piiia; ranbp2 usp9x ... See more keywords

YTHDF1 Aggravates the Progression of Cervical Cancer Through m6A-Mediated Up-Regulation of RANBP2

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Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.650383

Abstract: N6-methyladenosine (m6A) is the most common post-transcriptional modification of RNA in eukaryotes, which has been demonstrated to play important roles in various cancers. YTHDF1 acts as a crucial m6A “reader” and regulates the fate of… read more here.

Keywords: ythdf1; ranbp2; m6a; cervical cancer ... See more keywords