Multiple random phosphorylations in clock proteins provide long delays and switches
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-79277-z
Abstract: Theory predicts that self-sustained oscillations require robust delays and nonlinearities (ultrasensitivity). Delayed negative feedback loops with switch-like inhibition of transcription constitute the core of eukaryotic circadian clocks. The kinetics of core clock proteins such as… read more here.
Keywords: clock proteins; provide long; random phosphorylations; proteins provide ... See more keywords