Mendelian randomisation with coarsened exposures
Sign Up to like & getrecommendations! Published in 2021 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22376
Abstract: A key assumption in Mendelian randomisation is that the relationship between the genetic instruments and the outcome is fully mediated by the exposure, known as the exclusion restriction assumption. However, in epidemiological studies, the exposure… read more here.
Keywords: assumption; randomisation; exposure; mendelian randomisation ... See more keywords
Imbalance properties of centre-stratified permuted-block and complete randomisation for several treatments in a clinical trial.
Sign Up to like & getrecommendations! Published in 2017 at "Statistics in medicine"
DOI: 10.1002/sim.7206
Abstract: Randomisation schemes are rules that assign patients to treatments in a clinical trial. Many of these schemes have the common aim of maintaining balance in the numbers of patients across treatment groups. The properties of… read more here.
Keywords: trial; randomisation; permuted block; centre stratified ... See more keywords
On the importance of block randomisation when designing proteomics experiments.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.0c00536
Abstract: Randomisation is used in experimental design to reduce the prevalence of unanticipated confounders. Complete randomisation can however create unbalanced designs, for example, grouping all samples of the same condition in the same batch. Block randomisation… read more here.
Keywords: block randomisation; randomisation; designing proteomics; randomisation designing ... See more keywords
Embedded point of care randomisation for evaluating comparative effectiveness questions: PROSPECTOR-critical care feasibility study protocol
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-059995
Abstract: Introduction Many routinely administered treatments lack evidence as to their effectiveness. When treatments lack evidence, patients receive varying care based on the preferences of clinicians. Standard randomised controlled trials are unsuited to comparisons of different… read more here.
Keywords: randomisation; critical care; feasibility; care ... See more keywords
Vaccine testing for emerging infections: the case for individual randomisation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Ethics"
DOI: 10.1136/medethics-2015-103220
Abstract: During the 2014–2015 Ebola outbreak in Guinea, Liberia and Sierra Leone, many opposed the use of individually randomised controlled trials to test candidate Ebola vaccines. For a raging fatal disease, they explained, it is unethical… read more here.
Keywords: individual randomisation; trial; randomisation; emerging infections ... See more keywords
Merged block randomisation: A novel randomisation procedure for small clinical trials
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Trials"
DOI: 10.1177/1740774519827957
Abstract: Background/Aims: Randomisation in small clinical trials is a delicate matter, due to the tension between the conflicting aims of balanced groups and unpredictable allocations. The commonly used method of permuted block randomisation has been heavily… read more here.
Keywords: block randomisation; block; randomisation; merged block ... See more keywords
Community perspectives on randomisation and fairness in a cluster randomised controlled trial in Zambia
Sign Up to like & getrecommendations! Published in 2019 at "BMC Medical Ethics"
DOI: 10.1186/s12910-019-0421-7
Abstract: BackgroundOne important ethical issue in randomised controlled trials (RCTs) is randomisation. Relatively little is known about how participating individuals and communities understand and perceive central aspects of randomisation such as equality, fairness, transparency and accountability… read more here.
Keywords: randomised controlled; randomisation; cluster; randomisation process ... See more keywords
Reducing the Reality Gap Using Hybrid Data for Real-Time Autonomous Operations
Sign Up to like & getrecommendations! Published in 2023 at "Mathematics"
DOI: 10.3390/math11071696
Abstract: This paper presents an ablation study aimed at investigating the impact of a hybrid dataset, domain randomisation, and custom-designed neural network architecture on the performance of object localisation. In this regard, real images were gathered… read more here.
Keywords: randomisation; neural network; study; network architecture ... See more keywords