Frailty and cardiometabolic diseases: a bidirectional Mendelian randomisation study.
Sign Up to like & getrecommendations! Published in 2022 at "Age and ageing"
DOI: 10.1093/ageing/afac256
Abstract: BACKGROUND Frailty is strongly associated with cardiometabolic diseases in observational studies. However, whether the observed association reflects causality requires clarification. We performed a bidirectional Mendelian randomisation (MR) study to assess the causal relationship of frailty,… read more here.
Keywords: randomisation study; mendelian randomisation; frailty; bidirectional mendelian ... See more keywords
Genetic prediction of antihyperglycemic drug targets and risk of epilepsy: a mendelian randomisation study
Sign Up to like & getrecommendations! Published in 2024 at "BMC Pharmacology & Toxicology"
DOI: 10.1186/s40360-023-00718-2
Abstract: A connection between diabetes and an increased risk of epilepsy has been suggested by observational studies. Animal studies have also shown that antihyperglycemic drugs can improve seizures. However, it is unclear whether antihyperglycemic drugs have… read more here.
Keywords: mendelian randomisation; epilepsy; drug; risk epilepsy ... See more keywords