The effects of GLP-1 based therapies on postprandial haemodynamics: Two randomised, placebo-controlled trials in overweight type 2 diabetes patients.
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2016.12.011
Abstract: AIMS To assess the effects of glucagon-like peptide (GLP)-1 receptor agonists and dipeptidyl peptidase (DPP)-4 inhibitors on postprandial haemodynamics. METHODS 57 patients with type 2 diabetes (mean±SD age 62.8±6.9years; BMI 31.8±4.1kg/m2; HbA1c 7.3±0.6%) were included… read more here.
Keywords: index; placebo controlled; randomised placebo; postprandial haemodynamics ... See more keywords
Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): an international, randomised, placebo-controlled trial
Sign Up to like & getrecommendations! Published in 2018 at "The Lancet"
DOI: 10.1016/s0140-6736(18)30832-8
Abstract: BACKGROUND Myocardial injury after non-cardiac surgery (MINS) increases the risk of cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran prevents perioperative venous thromboembolism, but whether this drug can prevent a broader range of… read more here.
Keywords: non cardiac; trial; randomised placebo; cardiac surgery ... See more keywords
Long-term effects of a diet supplement containing Cannabis sativa oil and Boswellia serrata in dogs with osteoarthritis following physiotherapy treatments: a randomised, placebo-controlled and double-blind clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Research"
DOI: 10.1080/14786419.2022.2119967
Abstract: Abstract Dogs are commonly affected by Osteoarthritis (OA). Different approaches can be used to alleviate animals’ symptoms. In this randomised, placebo-controlled and double-blind clinical trial, we performed a three months follow-up study assessing the efficacy… read more here.
Keywords: controlled double; randomised placebo; double blind; placebo controlled ... See more keywords
Impact of novel glucose‐lowering therapies on physical function in people with type 2 diabetes: A systematic review and meta‐analysis of randomised placebo‐controlled trials
Sign Up to like & getrecommendations! Published in 2023 at "Diabetic Medicine"
DOI: 10.1111/dme.15083
Abstract: We investigated evidence from randomised, placebo‐controlled trials of novel glucose‐lowering therapies; sodium‐glucose co‐transporter‐2 inhibitors (SGLT2i), dipeptidyl peptidase‐4 inhibitors (DPP4i) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RA), on physical function in people with type 2 diabetes (T2D). read more here.
Keywords: controlled trials; randomised placebo; novel glucose; glucose lowering ... See more keywords
A double-blinded randomised placebo-controlled phase II trial to evaluate high dose rifampicin for tuberculous meningitis: a dose finding study
Sign Up to like & getrecommendations! Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01014-18
Abstract: High doses of rifampicin may help tuberculous meningitis (TBM) patients to survive. Pharmacokinetic-pharmacodynamic evaluations suggested that rifampicin doses higher than 13 mg/kg intravenously or 20 mg/kg orally (as previously studied) are warranted to maximize treatment… read more here.
Keywords: blinded randomised; double blinded; placebo controlled; randomised placebo ... See more keywords
Safety and efficacy of intravenous belimumab in children with systemic lupus erythematosus: results from a randomised, placebo-controlled trial
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-217101
Abstract: Objectives This ongoing Phase-2, randomised, placebo-controlled, double-blind study evaluated the efficacy, safety and pharmacokinetics of intravenous belimumab in childhood-onset systemic lupus erythematosus (cSLE). Methods Patients (5 to 17 years) were randomised to belimumab 10 mg/kg… read more here.
Keywords: placebo controlled; safety; randomised placebo; belimumab ... See more keywords
Effect of fenofibrate on plasma apolipoprotein C-III levels: a systematic review and meta-analysis of randomised placebo-controlled trials
Sign Up to like & getrecommendations! Published in 2018 at "BMJ Open"
DOI: 10.1136/bmjopen-2018-021508
Abstract: Objectives This meta-analysis of randomised placebo-controlled clinical trials aimed to assess the effect of fenofibrate on apolipoprotein C-III (apo C-III), a key regulator of triglyceride metabolism. Materials and methods Randomised placebo-controlled trials investigating the impact… read more here.
Keywords: iii; placebo controlled; analysis; randomised placebo ... See more keywords
Randomised, placebo-controlled, double-blind, double-dummy, multicentre trial comparing electronic cigarettes with nicotine to varenicline and to electronic cigarettes without nicotine: the ECSMOKE trial protocol
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Open"
DOI: 10.1136/bmjopen-2018-028832
Abstract: Introduction Electronic cigarettes (EC) mainly with nicotine content are widely used worldwide. Although the number of publications about its use is increasing exponentially, evidence-based, unbiased, conclusive, head-to-head comparisons about its efficacy and safety as an… read more here.
Keywords: trial; blind double; treatment; randomised placebo ... See more keywords
OASIS—a randomised, placebo-controlled trial of oral glucocorticoids for leg pain in patients with acute sciatica: trial protocol
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Open"
DOI: 10.1136/bmjopen-2020-040559
Abstract: Introduction Sciatica is a lower spine condition characterised by radiating leg pain below the knee. It may be accompanied by motor and sensory loss in the distribution of a spinal nerve. There are few effective… read more here.
Keywords: trial; placebo controlled; randomised placebo; leg pain ... See more keywords
COCOS trial: COrticosteroids for COVID-19-induced loss of Smell–protocol for a single-centred, double-blind, randomised, placebo-controlled trial
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-060416
Abstract: Introduction Hyposmia and anosmia are common in COVID-19. Most patients regain normal smell within 4 weeks, but severe loss of smell persists roughly in 20% after 2 months and may last up to a year or… read more here.
Keywords: randomised placebo; trial; smell; loss smell ... See more keywords
Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-061870
Abstract: Introduction Long COVID-19, where symptoms persist 12 weeks after the initial SARS-CoV-2-infection, is a substantial problem for individuals and society in the surge of the pandemic. Common symptoms are fatigue, postexertional malaise and cognitive dysfunction.… read more here.
Keywords: long covid; randomised placebo; trial; hyperbaric oxygen ... See more keywords