Adiponectin and the risk of gastrointestinal cancers in East Asians: Mendelian randomization analysis
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4735
Abstract: Adiponectin is an important adipocytokine and has been associated with the risks of gastrointestinal cancers (GICs). Mendelian randomization (MR) analysis is needed to assess the causal relationships between adiponectin and GICs. read more here.
Keywords: adiponectin; mendelian randomization; gastrointestinal cancers; randomization analysis ... See more keywords
Vitamin D, prediabetes and type 2 diabetes: bidirectional Mendelian randomization analysis
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nutrition"
DOI: 10.1007/s00394-019-01990-x
Abstract: Background Vitamin D deficiency is associated with glycemic dysregulation in many observational studies. However, the causality between them has not been fully established, especially in Asian origin. We used bidirectional Mendelian randomization (MR) analysis to… read more here.
Keywords: randomization analysis; mendelian randomization; bidirectional mendelian; type diabetes ... See more keywords
Hyperthyroidism and bone mineral density: Dissecting the causal association with Mendelian randomization analysis
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Endocrinology"
DOI: 10.1111/cen.14330
Abstract: Untreated hyperthyroidism is associated with accelerated bone turnover, low bone mineral density (BMD) and increased susceptibility to fragility fractures. Although treatment appears to improve or even reverse some of these adverse skeletal effects, there is… read more here.
Keywords: hyperthyroidism; bone mineral; randomization analysis; mendelian randomization ... See more keywords
Associations of Visceral Adipose Tissue, Circulating Protein Biomarkers, and Risk of Cardiovascular Diseases: A Mendelian Randomization Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.840866
Abstract: Aim: To evaluate the genetic associations of visceral adipose tissue (VAT) mass with metabolic risk factors and cardiovascular disease (CVD) endpoints and to construct a network analysis about the underlying mechanism using Mendelian randomization (MR)… read more here.
Keywords: disease; mendelian randomization; vat mass; randomization analysis ... See more keywords
Mendelian randomization analysis does not reveal a causal influence of mental diseases on osteoporosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1125427
Abstract: Introduction Osteoporosis (OP) is primarily diagnosed through bone mineral density (BMD) measurements, and it often leads to fracture. Observational studies suggest that several mental diseases (MDs) may be linked to OP, but the causal direction… read more here.
Keywords: mental diseases; mendelian randomization; risk; causal ... See more keywords
The Causal Evidence of Birth Weight and Female-Related Traits and Diseases: A Two-Sample Mendelian Randomization Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.850892
Abstract: Objectives : A large meta-analysis indicated a more pronounced association between lower birth weight (BW) and diseases in women but less concern about the causality between BW and female-related phenotypes and diseases. Methods: Mendelian randomization… read more here.
Keywords: female related; traits diseases; mendelian randomization; birth weight ... See more keywords
[Mendelian randomization analysis of the relationship between obesity and DNA methylation].
Sign Up to like & getrecommendations! Published in 2017 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.issn.0253-9624.2017.02.008
Abstract: Objective: To explore the association between DNA methylation and body mass index (BMI) using Mendelian randomization analysis. Methods: A total of 469 participants were selected from the Chinese National Twin Registry in 2013, who were… read more here.
Keywords: mendelian randomization; methylation; dna methylation; randomization analysis ... See more keywords