Causal relationship from coffee consumption to diseases and mortality: a review of observational and Mendelian randomization studies including cardiometabolic diseases, cancer, gallstones and other diseases
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nutrition"
DOI: 10.1007/s00394-021-02650-9
Abstract: High coffee consumption is associated with low risk of mortality and morbidity, but the causality remains unclear. This review aims to discuss findings from observational studies on coffee consumption in context of Mendelian randomization studies.… read more here.
Keywords: risk; randomization studies; mendelian randomization; coffee consumption ... See more keywords
Response to 'Challenge in interpretation of Mendelian randomization studies using lactase persistence as instrumental variable'
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DOI: 10.1038/ejcn.2017.119
Abstract: Response to 'Challenge in interpretation of Mendelian randomization studies using lactase persistence as instrumental variable' read more here.
Keywords: studies using; randomization studies; mendelian randomization; challenge interpretation ... See more keywords
Within family Mendelian randomization studies.
Sign Up to like & getrecommendations! Published in 2019 at "Human molecular genetics"
DOI: 10.1093/hmg/ddz204
Abstract: Mendelian randomization (MR) is increasingly used to make causal inferences in a wide range of fields, from drug development to aetiologic studies. Causal inference in MR is possible because of the process of genetic inheritance… read more here.
Keywords: randomization; randomization studies; mendelian randomization; family mendelian ... See more keywords
Accounting for antihypertensive medication in Mendelian randomization studies of blood pressure: methodological considerations in the Canadian Longitudinal Study on Aging.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of hypertension"
DOI: 10.1097/hjh.0000000000003464
Abstract: BACKGROUND Mendelian randomization (MR) studies investigating determinants of blood pressure (BP) do not account for antihypertensive medication consistently, which may explain discrepancies across studies. We performed an MR study of the association between body mass… read more here.
Keywords: medication; antihypertensive medication; randomization studies; mendelian randomization ... See more keywords
Which Risk Factors Causally Influence Dementia? A Systematic Review of Mendelian Randomization Studies
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DOI: 10.3233/jad-180013
Abstract: Background: Numerous risk factors for dementia are well established, though the causal nature of these associations remains unclear. Objective: To systematically review Mendelian randomization (MR) studies investigating causal relationships between risk factors and global cognitive… read more here.
Keywords: risk; randomization studies; mendelian randomization; risk factors ... See more keywords
Mendelian Randomization Studies on Nutritional Factors and Health Outcomes
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DOI: 10.3390/nu14142780
Abstract: Poor diet is a leading cause of morbidity and mortality [...]. read more here.
Keywords: nutritional factors; randomization studies; mendelian randomization; health outcomes ... See more keywords
An Overview of Methods and Exemplars of the Use of Mendelian Randomisation in Nutritional Research
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DOI: 10.3390/nu14163408
Abstract: Objectives: It is crucial to elucidate the causal relevance of nutritional exposures (such as dietary patterns, food intake, macronutrients intake, circulating micronutrients), or biomarkers in non-communicable diseases (NCDs) in order to find effective strategies for… read more here.
Keywords: relevance; randomization studies; mendelian randomization; nutritional exposures ... See more keywords