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Published in 2022 at "Journal of Biopharmaceutical Statistics"
DOI: 10.1080/10543406.2022.2094938
Abstract: ABSTRACT In this paper, we propose a randomized Bayesian optimal phase II (RBOP2) design with a binary endpoint (e.g., response rate). A beta-binomial distribution is used to model the binary endpoint for a two-arm phase…
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Keywords:
bayesian optimal;
randomized bayesian;
binary endpoint;
design ... See more keywords